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MetabolomicsOverexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees

Background

Bioconversion of wood into bioproducts and biofuels is hindered by the recalcitrance of woody raw material to bioprocesses such as enzymatic saccharification. Targeted modification of the chemical composition of the feedstock can improve saccharification but this gain is often abr...
2021-10-06 | MTBLS628 | MetaboLights
MetabolomicsA Cross-Platform Metabolomics Comparison Identifies Serum Metabolite Signatures of Liver Fibrosis Progression in Chronic Hepatitis C Patients
Metabolomics offers new insights into disease mechanisms that is enhanced when adopting orthogonal instrumental platforms to expand metabolome coverage, while also reducing false discoveries by independent replication. Herein, we report the first inter-method comparison when using multisegment injec...
2023-08-22 | MTBLS3111 | MetaboLights
TranscriptomicsLoss of the actin remodeler Eps8 causes calorie restriction and improved metabolic status in mice
In a variety of organisms, including mammals, caloric restriction improves metabolic status and lowers the incidence of chronic-degenerative diseases, ultimately leading to increased lifespan. Here we show that knockout mice for Eps8, a regulator of actin dynamics, display reduced bodyweight, partia...
ORGANISM(S): Mus musculus 
2010-03-09 | E-GEOD-14454 | biostudies-arrayexpress
OtherLysargiNase mirrors trypsin for protein C-terminal and methylation-site identification.
Data from ProteomeXchange: PXD ID: PXD001114. Experiment: LysargiNase, silac, file: LR_Ulilysin_PMA_A1_121126.mzml. Published as part of . From the Abstract: {{i}} To improve proteome coverage and protein C-terminal identification, we characterized the Methanosarcina acetivorans thermophilic protei...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310005457 | GPMDB
Resource Reanalysis 
TranscriptomicsTranscriptional profiling of immortalized LECs (imLECs)
In contrast to the migration of leukocytes from blood vessels into tissues, and the involvement of adhesion molecules and chemokines in this process, the migration of leukocytes from the tissue into lymphatic vessels is much less well understood. This can, in part be explained by the fact that murin...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-28234 | biostudies-arrayexpress
ProteomicsComprehensive characterization of Minichromosome Maintenance Complex (MCM) protein interactions using affinity and proximity purifications coupled to mass spectrometry.
This project is the complete interactome of the Minichromosome Maintenance (MCM) complex by using AP-MS and BioID approaches for all the different MCM proteins. Overall, our analysis identified unique and shared interaction partners and proteins enriched for distinct biological processes including D...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080198 | MassIVE
TranscriptomicsGlobal transcriptomic changes following N-deprivation in Nannochloropsis oceanica IMET1: Illumina sequencing
Limited systems-level understanding of oil synthesis in wild oleaginous algae has hindered the development of microalgal feedstock. Nannochloropsis is a small unicellular microalgae widely distributed in oceans and fresh water. In many large-scale and pilot-scale outdoor cultivation facilities, Nann...
ORGANISM(S): Nannochloropsis oceanica 
2014-05-14 | E-GEOD-42508 | biostudies-arrayexpress
TranscriptomicsMicroarray studies on genes stimulated by RANKL in bone marrow macrophages in a cyclooxygenase-2-dependent manner
Overall goal was to look for the differentially expressed genes between receptor activator of nuclear factor kappa-B ligand (RANKL)-stimulated wild type (WT) bone marrow macrophages (BMMs) and the BMMs in which the expression or the enzyme activity of cyclooxygenase-2 (Cox2), the major enzyme for pr...
ORGANISM(S): Mus musculus 
2016-01-07 | E-GEOD-72047 | biostudies-arrayexpress
TranscriptomicsProfiling of promoter occupancy by PPARM-NM-1 in human hepatoma cells via ChIP-chip analysis
The transcription factor Peroxisome Proliferator-Activated Receptor M-NM-1 (PPARM-NM-1) is an important regulator of hepatic lipid metabolism. While PPARM-NM-1 is known to activate transcription of numerous genes, no comprehensive picture of PPARM-NM-1 binding to endogenous genes has yet been report...
ORGANISM(S): Homo sapiens 
2010-11-23 | E-GEOD-25547 | biostudies-arrayexpress
TranscriptomicsER in Liver - 2
Liver transcriptome was analyzed at proestrus (P) and metestrus (M) in liver IGF-1-/- or LID mice. In order to elucidate the mechanism underlying ER control of liver metabolic function, we investigated the genetic programs controlled by the hepatic receptor during the physiological fluctuation of ci...
ORGANISM(S): Mus musculus 
2012-07-04 | E-MEXP-3505 | biostudies-arrayexpress
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