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Dysregulated Wnt signalling is seen in approximately 30% of hepatocellular cancers, thus finding pathways downstream of activation of Wnt signalling is key. Using cre lox technology we have deleted the the adenomatous polyposis coli tumour suppressor protein (Apc) within the adult mouse liver and ob...
ORGANISM(S): Mus musculus 
Wildtype C-Raf gene dosage and dimerization drive prostate cancer metastasis
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