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Analyse of gene expression modification after chronic analgesic treatment. The hypothesis tested in the present study was that oxycodone and morphine induced gene expression modification. Results provide important information to understand the analgesic effects of oxycodone as compared to morphine i...
ORGANISM(S): Rattus norvegicus 
The rising prevalence of opioid use during pregnancy poses serious public health concerns, yet the molecular mechanisms by which opioids such as oxycodone impact fetal development remain poorly understood. This study investigates the effects of chronic perinatal oxycodone exposure on the composition...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-27 | PXD065451 | Pride
Effects of oxycodone intake for HIV transgenic (Tg) rats
Maternal Oxycodone Treatment Causes Pathophysiological Changes in the Mouse Placenta
Behavioral flexibility and gut microbiome as potential predictors of oral oxycodone self-administration
Transcriptomic Changes in Mouse Trophoblast Cells Following Oxycodone Exposure
The purpose of this study is to test the oxycodone/naloxone combination compared to oxycodone alone in patient’s specific type of "chronic cancer pain".
Characterization of the intergenerational impact of in utero and postnatal oxycodone exposure
Prescription opioids such as oxycodone have been widely used in the United States and have contributed to the ongoing opioid epidemic. While many individuals limit use to prescribed contexts, a subset transitions to misuse and, in some cases, to illicit opioid use. Identifying behavioral and biologi...
ORGANISM(S): feces metagenome 
2026-04-03 | GSE326997 | GEO
The primary objective of this trial is to study the efficacy of oxycodone/naloxone prolonged release tablets (OXN PR), compared to oxycodone prolonged release tablets (Oxy PR), for the reduction of the intensity of opioid-induced constipation symptoms in patients treated for cancer or non-cancer pai...
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