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MetabolomicsUrea cycle and 1C/serine metabolism in the prevention of oxygen induced retinopathy
Not available
ORGANISM(S): Mus musculus 
ST001130 | MetabolomicsWorkbench
MetabolomicsOxygen-induced pathological angiogenesis promotes intense lipid synthesis and remodeling in the retina

The retina is a notable tissue with high metabolic needs which relies on specialized vascular networks to protect the neural retina while maintaining constant supplies of oxygen, nutrients and dietary essential fatty acids. Here we analyzed the lipidome of the mouse retina under healthy and patho...

2023-05-09 | MTBLS6965 | MetaboLights
MetabolomicsModification of erythrocyte membrane phospholipid composition in preterm newborns with retinopathy of prematurity: The omegaROP study

N-3 polyunsaturated fatty acids (PUFAs) may prevent retinal vascular abnormalities observed in oxygen-induced retinopathy, a model of retinopathy of prematurity (ROP). In the OmegaROP prospective cohort study, we showed that preterm infants who will develop ROP accumulate the n-6 PUFA arachidonic...

2022-09-07 | MTBLS4219 | MetaboLights
MetabolomicsSerine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity
We determined which metabolic pathways are activated by hypoxia-inducible factor 1-mediated (HIF-1-mediated) protection against oxygen-induced retinopathy (OIR) in newborn mice, the experimental correlate to retinopathy of prematurity, a leading cause of infant blindness. HIF-1 coordinates the chang...
2019-07-05 | MTBLS856 | MetaboLights
TranscriptomicsGene expression microarray analysis of early oxygen-induced retinopathy (OIR)
Different inbred strains of rats differ in their susceptibility to OIR, an animal model of human retinopathy of prematurity. We examined gene expression profiles in Fischer 344 (F344, resistant to OIR) and Sprague Dawley (SD, susceptible to OIR) rats at the early time point of day 3 to identifying g...
ORGANISM(S): Rattus norvegicus 
2009-11-12 | E-GEOD-18998 | biostudies-arrayexpress
GenomicsEffects of inhibitors in mice with oxygen-induced retinopathy
Effects of inhibitors in mice with oxygen-induced retinopathy
PRJNA962098 | ENA
GenomicsC57Bl6J retina lysates in oxygen-induced retinopathy
C57Bl6J retina lysates in oxygen-induced retinopathy
PRJNA666571 | ENA
GenomicsMurine model of oxygen-induced retinopathy - 3 time points [blood]
Murine model of oxygen-induced retinopathy - 3 time points [blood]
PRJNA537864 | ENA
GenomicsMurine model of oxygen-induced retinopathy - 3 time points [retina]
Murine model of oxygen-induced retinopathy - 3 time points [retina]
PRJNA539988 | ENA
GenomicsmicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model
microRNA expression profile in retina and choroid in oxygen-induced retinopathy model
PRJNA533461 | ENA
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