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UnknownA Mutant RNA Polymerase Activates the General Stress Response, Enabling Escherichia coli Adaptation to Late Prolonged Stationary Phase.
Not available
S-EPMC7160681 | biostudies-literature
MetabolomicsThe Leiden Longevity Study: Identification of biomarkers of the rate of ageing
The aim of the study is to identify genetic mechanisms of longevity and to characterize their interaction with the environment. Using the results the future health of people without familial longevity can be improved in old age. Long-lived siblings of European descent were recruited together with th...
2019-07-11 | MTBLS974 | MetaboLights
UnknownContext-dependent conservation of DNA methyltransferases in bacteria.
Not available
S-EPMC3424554 | biostudies-literature
UnknownGenomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli.
Not available
S-EPMC4263303 | biostudies-literature
GenomicsSigma38 binding sites in E. Coli
ChIP-seq to identify sigma38 binding sites in wild-type and delta ssrS (6S RNA knockout) strains of E. Coli K-12 MG1655, during stationary phase ChIP-seq using antibody against sigma38 in wild-type and ssrS deletion strain. Two replicates for wild type and one replicate for ssrS deletion.
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2016-06-10 | E-GEOD-74836 | biostudies-arrayexpress
GenomicsChIP-seq of E. coli to identify H-NS and Fis binding at multiple time-points during growth in rich medium
Among the most important regulators of gene expression in bacteria are 'nucleoid-associated proteins'. These proteins alter the topology of the bound DNA by bending, wrapping or bridging it, thus having multiple effects, including transcriptional regulation, on the bacterial cell. Among the best-stu...
ORGANISM(S): Escherichia coli 
2010-09-01 | E-MTAB-332 | biostudies-arrayexpress
TranscriptomicsA High-Fat Diet and NAD+ Rescue Premature Aging in Cockayne Syndrome
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in the genes encoding the DNA repair proteins CSA or CSB. Csbm/m mice were given a high-fat, caloric-restricted or resveratrol-supplemented diet. The high-fat diet rescued the p...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-62194 | biostudies-arrayexpress
UnknownDiversity and spatiotemporal distribution of mosquitoes (Diptera: Culicidae) with emphasis on disease vectors across agroecological areas of Kerala, India.
Not available
S-EPMC12368041 | biostudies-literature
TranscriptomicsMicroarray expression profiling of male and female bone marrow derived macrophages from wild type and lysMCre/Irf2bp2flox mice
Interferon regulatory factor 2 binding protein 2 (Irf2bp2) is a corepressor of Irf2 that suppresses inflammatory gene expression and promotes the M2 macrophage phenotype in bone marrow derived macrophages (BMDM). Loss of Irf2bp2 in male macrophages promotes an inflammatory phenotype. Here, we compar...
ORGANISM(S): Mus musculus domesticus 
2024-09-01 | E-MTAB-14166 | biostudies-arrayexpress
UnknownA regulatory module mediating temperature control of cell-cell communication facilitates tree bud dormancy release
Not available
S-SCDT-10_1038-S44318-024-00256-5 | biostudies-other
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