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MetabolomicsUnveiling molecular changes in guabiju during Aspergillus brasiliensis cultivation: insights from untargeted metabolomics

Black aspergilli exhibit remarkable bioconversion potential by transforming plant matrices into bioactive compounds, although their metabolic processes remain underexplored. This study investigated the biotransformation of metabolites during the solid-state cultivation of guabiju (Myrcianthes...

2025-08-08 | MTBLS12436 | MetaboLights
TranscriptomicsGene expression modulation by paraquat-induced oxidative stress conditions in P. brasiliensis
Paracoccidioides brasiliensis is a thermodimorphic fungus associated with paracoccidioidomycosis (PCM), the most common systemic mycosis in Latin America. The infection is initiated by inhalation of environmental dispersed conidia produced by the saprophytic phase of the fungus. In the lungs, P. bra...
ORGANISM(S): Paracoccidioides brasiliensis 
2013-06-14 | E-GEOD-41148 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mycelium and yeast cells of Paracoccidioides brasiliensis
Identification of differential mRNAs produced in the mycelium and yeast cells of Paracoccidioides brasiliensis
ORGANISM(S): Paracoccidioides brasiliensis 
2004-04-28 | E-MEXP-103 | biostudies-arrayexpress
no omics definedTranscription profiling of Paracoccidioides brasiliensis yeast cells grown inside murine macrophages and in vitro
Gene expression comparison of P. brasiliensis yeast cells grown in two differente conditions: inside murine macrophage and in vitro
ORGANISM(S): Paracoccidioides brasiliensis 
2006-09-22 | E-MEXP-823 | biostudies-arrayexpress
TranscriptomicsDNA microarray comparison of gene expression patterns in Paracoccidioides brasiliensis mycelia and yeasts in vitro.
Paracoccidioides brasiliensis is a thermally dimorphic fungus, which causes the most prevalent systemic mycosis in Latin America. Infection is initiated by inhalation of conidia or mycelial fragments by the host, followed by further differentiation into the yeast form. Information regarding gene e...
ORGANISM(S): Paracoccidioides brasiliensis 
2009-05-07 | E-GEOD-15511 | biostudies-arrayexpress
ProteomicsPhosphosite-specific regulation of the oxidative-stress response of P. brasiliensis: A Shotgun Phosphoproteomic Analysis
Paracoccidioides brasiliensis, a thermally dimorphic fungus, is the causative agent of paracoccidioidomycosis, a systemic mycosis that is widespread in Latin America. P. brasiliensis infection occurs when conidia or mycelial fragments are inhaled by the host, which causes these cells to transition t...
ORGANISM(S): Paracoccidioides brasiliensis (strain Pb18) 
2022-03-03 | PXD001181 | Pride
Paracoccidioides brasiliensis Post-translational modification Cell proliferation Phosphorylation Oxidative stress 
ProteomicsExtracellular vesicules proteomic profile of P. brasiliensis yeasts recovered from granulomatous lesions of C57BL/6 WT mice
C57BL/6 WT mice were infected with 1x10^6 P. brasiliensis yeasts. After 8 weeks and 12 weeks of infection the animals were euthanized and the granulomatous lesions were recovered. Then, the yeasts were recovered and cultivated in a rich medium. After cultivation the yeasts extracellular vesicles wer...
ORGANISM(S): Paracoccidioides brasiliensis (strain Pb18) 
2024-05-23 | PXD046549 | Pride
Paracoccidioides brasiliensis  extracellular vesicles  granuloma 
ProteomicsProteomic analysis of proteome of THP-1 macrophages incubated with Paracoccidioides brasiliensis yeast cells alive or heat-killed
Paracoccidioides spp. is the etiological agent of Paracoccidioidomycosis (PCM), a systemicinfection with wide distribution in Latin America. Macrophages are very important cells during the response to infection by Paracoccidoides brasiliensis and understanding the interaction between the fungus and ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-23 | PXD043727 | Pride
P. brasiliensis  proteomic analysis  metabolic reprogramming  immunometabolism 
ProteomicsProteomic profile of P. brasiliensis yeasts recovered from granulomatous lesions of C57BL/6 WT mice
C57BL/6 WT mice were infected with 1x10^6 P. brasiliensis yeasts. After 8 weeks and 12 weeks of infection the animals were euthanized and the granulomatous lesions were recovered. Then, the yeasts were recovered and cultivated in a rich medium. After cultivation the yeasts proteins were extracted, d...
ORGANISM(S): Paracoccidioides brasiliensis (strain Pb18) 
2023-10-23 | PXD040829 | Pride
Paracoccidioidomycosis  granuloma  proteomic  paracoccidioides brasiliensis 
ProteomicsExploring potential virulence regulators in Paracoccidioides brasiliensis isolates of varying virulence through quantitative proteomics
Paracoccidioides brasiliensis is the agent of paracoccidioidomycosis, an important systemic mycosis in Latin America. Few virulence factors have been identified for this pathogen. In this study, we quantitatively evaluated the protein composition of P. brasiliensis in the yeast phase using minimal a...
ORGANISM(S): Paracoccidioides brasiliensis (strain Pb18) 
2014-08-28 | PXD000804 | Pride
Paracoccidioides brasiliensis  pathogenic fungus  proteomic analysis  virulence regulators 
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