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ProteomicsPulldown of P180/RRBP1 interacting protein
P180/RRBP1 is an integral ER-resident protein known to be involved in mRNA binding and translation at the ER. We found that P180/RBBP1 is enriched in neuronal axons. To acquire more knowledge about its interactome and confirmation that P180/RRBP1 is interacting with ribosomes, we performed an unbias...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2024-10-14 | PXD050948 | Pride
Brain P180/rrbp1 Hek293 
GenomicsAxonal ER tubules control local translation via P180/RRBP1-mediated ribosome interactions
Axonal ER tubules control local translation via P180/RRBP1-mediated ribosome interactions
PRJNA1090922 | ENA
UnknownAxonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions.
Not available
S-EPMC11338522 | biostudies-literature
TranscriptomicsAxonal ER tubules control local translation via P180/RRBP1-mediated ribosome interactions
Local mRNA translation in axons is critical for the spatial and temporal regulation of the axonal proteome. A wide variety of mRNAs are localized and translated in axons, however how protein synthesis is regulated at specific subcellular sites in axons remains unclear. Here, we establish that the ax...
ORGANISM(S): Rattus norvegicus 
2024-04-29 | GSE262262 | GEO
ProteomicsPERK crosstalk between ER and microtubule dynamics
The architecture of the endoplasmic reticulum (ER) is tightly controlled as a key determinant of its function. Its dynamics are linked to those of the cytoskeleton, but our understanding of how this coordination occurs and what its functional relevance is, is limited. We found the Unfolded Protein R...
ORGANISM(S): Homo sapiens (Human) 
2025-11-03 | PXD057012 | Pride
Human Endoplasmic reticulum (er) Unfolded protein response 
UnknownmRNA encoding Sec61β, a tail-anchored protein, is localized on the endoplasmic reticulum.
Not available
S-EPMC4582399 | biostudies-literature
UnknownPERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape.
Not available
S-EPMC12548782 | biostudies-literature
TranscriptomicsOpossum RNA-seq time-series of the development of seven major organs
This dataset covers the development of 7 organs (brain, cerebellum, heart, kidney, liver, ovary and testis) from embryonic day 13.5 to adulthood.
ORGANISM(S): Monodelphis domestica 
2019-02-18 | E-MTAB-6833 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of the AD11 anti-NGF transgenic mouse model of neurodegeneration at 1, 3, 6, 15 months of age
We characterized the gene expression profile of brain regions at different stages of the AlzheimerM-bM-^@M-^Ys like neurodegeneration in the anti-NGF AD11 trangenic mouse model. Total RNA was extracted from hippocampus, cortex and basal forebrain of postnatal day 30 (P30, 1 month), P90 (3 months), P...
ORGANISM(S): Mus musculus 
2015-02-26 | E-GEOD-63617 | biostudies-arrayexpress
MetabolomicsDistinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones

INTRODUCTION: Prostatitis is likely to occur in younger or middle-aged men, while prostate cancer is likely to occur in older men. Although amino acids and lipids as biomarkers of prostate cancer have been examined using prostate cancer cell lines/tissues, no previous studies hav...

2020-11-04 | MTBLS2028 | MetaboLights
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