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ProteomicsAn mRNA-based workflow for validation of Neo-Epitope Presentation by HLA-I/Peptide Affinity Purification
Human leukocyte antigen (HLA) class I restricted neo-epitopes play a key role in inducing an adaptive cytotoxic T lymphocyte response against cancer. To enhance therapeutic and personalized cancer vaccination strategies, the identification of these cancer-specific neo-epitopes is essential. Current ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-23 | PXD062551 | Pride
P53 epitope Hla-a*0201 Immunopeptidomics Mrna 
ProteomicsNucleic Acid Programmable Protein Arrays (NAPPA) Somatic p53 Mutations
Purpose: Mutations in TP53 induce autoantibody immune responses in a subset of cancer patients, which have been proposed as biomarkers for early detection. Here, we investigate the association of p53 specific autoantibodies with multiple tumor subtypes and determine the association with p53 mutation...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-77949 | biostudies-arrayexpress
UnknownA small epitope shared by p53 and an unrelated protein upregulated after adenovirus infection.
Not available
S-EPMC10168313 | biostudies-literature
TranscriptomicsTranscription profiling of human HeLa CD4+ cells transfected with epitope-tagged eTat plasmid, or parental plasmid pCep4
Expression profiles of HeLa CD4+ cells transfected with epitope-tagged eTat plasmid, or parental plasmid pCep4. Cells are unsynchronized and untreated.
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-570 | biostudies-arrayexpress
UnknownA novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53.
Not available
S-EPMC2988382 | biostudies-literature
ProteomicsNucleic Acid Programmable Protein Arrays (NAPPA) Somatic p53 Mutations
Purpose: Mutations in TP53 induce autoantibody immune responses in a subset of cancer patients, which have been proposed as biomarkers for early detection. Here, we investigate the association of p53 specific autoantibodies with multiple tumor subtypes and determine the association with p53 mutation...
ORGANISM(S): Homo sapiens 
2016-06-01 | GSE77949 | GEO
TranscriptomicsBaculovirus-encoded protein expression for epigenomic profiling in Drosophila cells
Baculovirus-encoded proteins can be efficiently produced following infection of different Drosophila cell lines. Epitope-tagged proteins produced in baculovirus-infected cells provide genome-wide profiles of the histone variant H2Av that are comparable to those produced by stably transformed cell li...
ORGANISM(S): Drosophila melanogaster 
2010-07-12 | E-GEOD-21416 | biostudies-arrayexpress
UnknownAnti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth.
Not available
S-EPMC3759663 | biostudies-literature
UnknownProteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers.
Not available
S-EPMC5553208 | biostudies-literature
GenomicsRemodeling of anti-tumor immunity with antibodies targeting a p53 mutant
Remodeling of anti-tumor immunity with antibodies targeting a p53 mutant
PRJNA1083988 | ENA
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