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ProteomicsIdentification of p85beta protein interaction partners in ovarian cancer cells
p85beta is one of the regulatory subunits of the PI3K. Apart from its canonical role in binding to and regulating the p110 catalytic subunit, the protein may bind to other interacting proteins to perform other biological functions. In this study, the protein binding partners of p85beta were determin...
ORGANISM(S): Homo sapiens (Human) 
2024-12-23 | PXD052205 | Pride
Ip-ms Pi3k P85beta Immunoprecipitation-mass spectrometry 
GenomicsIdentification of p85beta- or BCLAF1-enriched genomic regions
Identification of p85beta- or BCLAF1-enriched genomic regions
PRJNA1108594 | ENA
GenomicsGenes co-regulated by p85beta and BCLAF1 in ovarian cancer cells
Genes co-regulated by p85beta and BCLAF1 in ovarian cancer cells
PRJNA1107399 | ENA
GenomicsIdentification of p85beta- or BCLAF1-enriched genomic regions
p85beta of the PI3K can localize to the nucleus. Our immunoprecipitation data showed that it physically interacts with a transcription factor BCLAF1. To reveal the enrichment of p85beta and BCLAF1 at genomic regions and to determine whether p85beta and BCLAF1 co-occupy at genomic regions, chromatin ...
ORGANISM(S): Homo sapiens 
2024-12-25 | GSE266856 | GEO
TranscriptomicsGenes co-regulated by p85beta and BCLAF1 in ovarian cancer cells
p85beta of the PI3K can localize to the nucleus. Our data showed that it can increase the expression of a transcription factor BCLAF1. To determine whether p85beta has any affect on gene transcription and to identify gene targets that are regulated through BCLAF1, RNAseq was performed on p85beta-exp...
ORGANISM(S): Homo sapiens 
2024-12-25 | GSE266499 | GEO
Unknownp85beta phosphoinositide 3-kinase regulates CD28 coreceptor function.
Not available
S-EPMC2945823 | biostudies-literature
UnknownInfluenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling.
Not available
S-EPMC1599933 | biostudies-literature
UnknownThe regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation.
Not available
S-EPMC3071012 | biostudies-literature
UnknownPhosphoinositide 3-kinase p85beta regulates invadopodium formation.
Not available
S-EPMC4197441 | biostudies-literature
UnknownStructural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein.
Not available
S-EPMC2808220 | biostudies-literature
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