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MetabolomicsMetabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Interspecific chemical variability assay)

The biogeography of tropical Andean plants and the effects of altitudinal barriers as evolutionary constraints have been the focus of great debate. Although genetic markers have provided evidence for the geographic isolation of Andean-endemic groups, even highly variable molecular markers commonl...

2020-03-24 | MTBLS944 | MetaboLights
MetabolomicsMetabolomic evidence for biogeographic segregation in Espeletiinae (Asteraceae): A new perspective on an Andean adaptive radiation in sky islands (Intraspecific chemical variability assay)

The biogeography of tropical Andean plants and the effects of altitudinal barriers as evolutionary constraints have been the focus of great debate. Although genetic markers have provided evidence for the geographic isolation of Andean-endemic groups, even highly variable molecular markers commonl...

2020-03-24 | MTBLS943 | MetaboLights
MetabolomicsBiogeography shaped the metabolome of the genus Espeletia: a phytochemical perspective on an Andean adaptive radiation
The páramo ecosystem has the highest rate of diversification across plant lineages on earth, of which the genus Espeletia (Asteraceae) is a prime example. The current distribution and molecular phylogeny of Espeletia suggest the influence of Andean geography and past climatic fluctuations on the div...
2018-11-20 | MTBLS445 | MetaboLights
TranscriptomicsImpact of exercise training on endothelial transcriptional profiles in healthy swine: A genome-wide microarray analysis
While the salutary effects of exercise training on conduit artery endothelial cells have been reported in animals and humans with cardiovascular risk factors or disease, whether a healthy endothelium is alterable with exercise training is less certain. The purpose of this study was to evaluate the ...
ORGANISM(S): Sus scrofa 
2011-12-02 | E-GEOD-26663 | biostudies-arrayexpress
MetabolomicsInsights into Metabolic Changes Caused by the Trichoderma virens-Maize Root Interaction
The interactions of crops with root-colonizing endophytic microorganisms are highly relevant to agriculture, because endophytes can modify plant resistance to pests and increase crop yields. We investigated the interactions between the host plant Zea mays and the endophytic fungus Trichode...
2021-07-08 | MTBLS1964 | MetaboLights
TranscriptomicsGene expression changes in the fetal rhesus monkey uterus from early to late gestation and the effects of in utero exposure to BPA
We used the rhesus monkey (Macaca mulatta) as our animal model for the current study with two goals: to characterize the changes in histology and gene expression from early to late gestation (prenatal uterine organogenesis) and to determine if there are effects of prenatal exposure to bisphenol A (B...
ORGANISM(S): Macaca mulatta 
2014-05-22 | E-GEOD-38421 | biostudies-arrayexpress
TranscriptomicsMolecular Characterization of Spontaneously Transformed Epithelial Murine Colon Cell Lines as a Model of Human Colorectal Neoplasia (CGH)
To characterize a series of mouse colon cells that have become spontaneously transformed over time in order to identify the chromosomal and genomic alterations that take place during the development of tumorigenesis. Colorectal cancer is the third common malignancy in the United States. The stepwise...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-70790 | biostudies-arrayexpress
TranscriptomicsJuvenile obesity in Ossabaw swine produces artery-specific transcriptional changes
We adopted a transcriptome-wide microarray analysis approach to determine the extent to which vascular gene expression is altered as a result of juvenile obesity and identify obesity-responsive mRNAs. We examined transcriptional profiles in the left anterior descending coronary artery (LAD), perivas...
ORGANISM(S): Sus scrofa 
2013-05-29 | E-GEOD-41636 | biostudies-arrayexpress
UnknownInhibition of a conserved bacterial dual-specificity phosphatase confers plant tolerance to Candidatus Liberibacter spp.
Not available
S-EPMC10904284 | biostudies-literature
MetabolomicsMetabolomic and gene expression approaches reveal the developmental and environmental regulation of the secondary metabolism of yacón (Smallanthus sonchifolius, Asteraceae)
Acting as chemical defense or signaling compounds, secondary metabolites (SMs) play an essential role in the evolutionary success of many angiosperm plant families. However, the adaptive advantages that SMs confer, and the influence of environmental and developmental factors on SMs expression, remai...
2020-03-24 | MTBLS840 | MetaboLights
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