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UnknownPrenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study.
Not available
S-EPMC6386638 | biostudies-literature
TranscriptomicsEffects of resistance exercise on the transcriptome in MHC I and MHC IIa muscle fibers of young and old women
Global microarray (HG U133 Plus 2.0) was used for the first time to investigate the effects of resistance exercise on the transcriptome in slow-twitch myosin heavy chain (MHC) I and fast-twitch MHC IIa muscle fibers of young and old women. Vastus lateralis muscle biopsies were obtained pre and 4hrs...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-28392 | biostudies-arrayexpress
TranscriptomicsGene expression in blastomeres after transfer of somatic cells into human oocytes
The exchange of the oocyte's genome with the genome of a somatic cell, followed by the derivation of pluripotent stem cells, could enable the generation of specific cell types affected in degenerative human diseases. Such cells, carrying the patient's genome, might be useful for cell replacement. H...
ORGANISM(S): Homo sapiens 
2011-10-05 | E-GEOD-28022 | biostudies-arrayexpress
GenomicsAmplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint
Exogenous double-stranded RNA (dsRNA) has been shown to exert homology-dependent effects at the level of both target mRNA stability and chromatin structure. Using C. elegans undergoing RNAi as an animal model, we have investigated the generality, scope, and longevity of chromatin-targeted dsRNA effe...
ORGANISM(S): Caenorhabditis elegans 
2012-01-06 | E-GEOD-32631 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of Leishmania mexicana wild type and glucose transporter (lmgt) knock-out strains show genomic adaptation
Genomic adaptation following glucose transporter knockout in leishmania mexicana
ORGANISM(S): Leishmania mexicana 
2008-12-01 | E-MEXP-1858 | biostudies-arrayexpress
TranscriptomicsA nuclear Argonaute promotes germline immortality and epigenetic inheritance across generations
dsRNA-mediated gene silencing (RNAi) can be inherited for multiple generations in C. elegans. To understand this process we conducted a genetic screen for animals defective for transmitting RNAi silencing signals to future generations. This screen identified the gene heritable RNAi defective (hrde)-...
ORGANISM(S): Caenorhabditis elegans 
2012-07-30 | E-GEOD-38041 | biostudies-arrayexpress
TranscriptomicsHuman Promoters Are Intrinsically Directional
Divergent transcription, in which reverse-oriented transcripts occur upstream of eukaryotic promoters in regions devoid of annotated genes, has been suggested to be a general property of active promoters. Here we show that the human basal RNA polymerase II transcriptional machinery and core promoter...
ORGANISM(S): Homo sapiens 
2015-01-16 | E-GEOD-63872 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD14+ monocytes treated with innate defence regulator peptide IDR-1 in the presence/absence of lipopolyssacharide
Effect of peptide IDR-1 on CD14+ human monocytes. >br< >br< Effect of peptide IDR-1 on LPS-induced responses in CD14+ human monocytes.>br< >br< Human peripheral blood mononuclear cells (PBMC) were treated with innate defence regulator peptide IDR-1 in the presence and absence of LPS (purified from P...
ORGANISM(S): Homo sapiens 
2007-04-10 | E-FPMI-8 | biostudies-arrayexpress
UnknownEffect of Probiotics on Incident Ventilator-Associated Pneumonia in Critically Ill Patients: A Randomized Clinical Trial.
Not available
S-EPMC8456390 | biostudies-literature
UnknownRisk for non-home discharge following surgery for ischemic mitral valve disease.
Not available
S-EPMC7874266 | biostudies-literature
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