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ProteomicsA stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses
Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified as a human pathogen in 2012 and causes ongoing sporadic infections and outbreak clusters. Despite case fatality rates (CFRs) of over 30% and the pandemic potential associated with betacoronaviruses, a safe and efficacious v...
ORGANISM(S): Homo sapiens (Human) 
2026-01-14 | PXD059802 | Pride
ProteomicsA Long-Range Recruitment Mechanism for mTORC2 Phosphorylation of Akt
Study of the phosphorylation of human Akt1 (Akt) by mTOR complex 2 (mTORC2) in vitro. Akt was prepared by semi-synthesis, resulting in a non-phosphorylated C-tail, allowing unbiased study of the sites phosphorylated by mTORC2. Because enzymologic data showed that the canonical hydrophobic motif resi...
ORGANISM(S): Homo sapiens (Human) 
2026-02-02 | PXD048719 | Pride
Akt Agc kinase Mtorc2 Mtor Phosphorylation Hydrophobic motif 
ProteomicsAn efficient urine peptidomics workflow identifies chemically defined dietary gluten peptides from patients with celiac disease
This study sought to identify proteins derived from dietary wheat, rye, and barley in human urine samples. The urinary peptidomes of celiac disease patients and healthy controls were compared.
ORGANISM(S): Homo sapiens (Human) Triticum aestivum (Wheat) Hordeum vulgare (Barley) Secale cereale 
2022-01-18 | PXD031048 | Pride
Peptidomics Urine Celiac disease Wheat 
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