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ProteomicsPan-cancer and multi-omics analyses reveal the diagnostic and prognostic value of BAZ2B
The BAZ2B gene belongs to the bromodomain gene family. The proteins encoded by members of this gene family are important components of chromatin remodelling complexes and have a potential role in transcriptional activation. However, the biological significance of BAZ2B in pan-cancer is unknown. In t...
ORGANISM(S): Homo Sapiens 
PXD054319 |
ProteomicsProteomic and phosphoproteomic analyses for HT-29
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo sapiens (Human) 
2025-02-28 | PXD058218 | Pride
Cbx8 Phosphoproteomic Proteomic Plk1 
ProteomicsSynthetic lethal combinations targeting PLK1-CBX8-GPX4 axis with BRAF and EGFR inhibition in BRAF V600E colorectal cancer
Metastatic BRAFV600E colorectal cancer (CRC) confers poor prognosis and run into a bottleneck in the current treatment strategies. To identify regulatory pathways independent of the MAPK pathway in BRAFV600E CRC, we performed CRISPR-Cas9 screening, and and find targeting glutathione peroxidase 4 (GP...
ORGANISM(S): Homo Sapiens 
2024-11-25 | PXD058213 |
UnknownFactors associated with glycemic control in community-dwelling elderly individuals with type 2 diabetes mellitus in Zhejiang, China: a cross-sectional study.
Not available
S-EPMC6555723 | biostudies-literature
UnknownEnterotypes in asthenospermia patients with obesity.
Not available
S-EPMC9550853 | biostudies-literature
MetabolomicsExploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors.

The gut microbiome has emerged as a potential factor in cancer pathogenesis, but its role in non-functioning pituitary neuroendocrine tumors (NF-PitNETs) remains unclear. This study aimed to elucidate gut microbiome and metabolomic alterations in NF-PitNETs by comparing microbial diversity, patho...

2025-06-16 | MTBLS12328 | MetaboLights
UnknownGenetic landscape of human oocyte/embryo defects
Not available
S-EPMC12926087 | biostudies-literature
ProteomicsComparison of the ability of exosomes and ectosomes derived from mesenchymal stem cells to promote cartilage regeneration in a rat osteochondral defect model
Background: Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) offer promising prospects for stimulating cartilage regeneration. The different formation mechanisms suggest that exosomes and ectosomes possess different biological functions. However, little attention has been paid...
ORGANISM(S): Rattus Rattus 
PXD041283 |
ProteomicsProteomic analysis of YexiangB and the OsMKK3 mutant line
TMT-based quantitative proteomic analysis of YexiangB and the OsMKK3 mutant line to obtain regulated proteins
ORGANISM(S): Oryza Sativa 
2022-11-09 | PXD038056 |
ProteomicsDecoding the Femoral and Tibial Entheses of the Human Anterior Cruciate Ligament
To analyze the location-specific graduated mineral composition and assembly, and mechanical transitions of the FE and TE in human knee joints.
ORGANISM(S): Homo Sapiens 
PXD056631 |
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