Despite advances in the development of direct KRAS inhibitors, KRAS-mutant cancers continue to exhibit resistance to the currently available therapies. Here, we identified REGγ as a mutant KRAS-associated factor that enhances REGγ transcription through the KRAS intermediate NRF2, suggesting that the...
There are the raw data of Kme1 peptides identification in the paper titled "A Chemoselective Enrichment Strategy for In-Depth Coverage of the Methyllysine Proteome".
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090)
An experiment was performed to study positive selection on expression regulation in human tissues by comparing expression values in humans to those in chimpanzees, orangutans and rhesus macaques.
