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UnknownCross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions.

Background

Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and Drug Administration-led SEquence Quality Control project phase2 (SEQC2) ...
S-EPMC8051090 | biostudies-literature
ProteomicsThe pan-cancer lncRNA PLANE regulates an alternative splicing program and promotes cancer pathogenesis
Proteome analysis of Biotin- PLANE pull-down assays
ORGANISM(S): Homo Sapiens 
2020-11-26 | PXD022747 |
ProteomicsIntegrated Proteogenomic Characterization of Localized Prostate Cancer Identifies Biological Insights and Subtype-Specific Therapeutic Strategies
We profiled the genome, transcriptome, proteome and phosphoproteome of 145 cases of localized prostate cancer (PCa) in Chinese patients and revealed three subtypes with distinct molecular features. We integrated multi-omic data to refine molecular subtyping of localized PCa, and identified NANS as a...
ORGANISM(S): Homo Sapiens 
PXD056748 |
ProteomicsProteomics of prostate cancer cell lines
We profiled the proteomics of prostate cancer (PCa) cell lines.
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-12-06 | PXD058635 |
ProteomicsProteomics of prostate cancer orthotopic transplanted mice
We profiled the proteomics of prostate cancer orthotopic transplanted mice.
ORGANISM(S): Mus Musculus 
2025-01-21 | PXD058636 |
UnknownAwareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic: A cross-sectional survey across 57 countries.

Background

Since the COVID-19 pandemic began, there have been concerns related to the preparedness of healthcare workers (HCWs). This study aimed to describe the level of awareness and preparedness of hospital HCWs at the time of the first wave.

Methods

This multinational, multicenter...
S-EPMC8694437 | biostudies-literature
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