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We sequenced 205 patients who were suffering NSCLC with Exome sequencing method.
We sequenced 292 patients who were suffering NSCLC with Whole genome sequencing or Exome sequencing method.
Data Access Committee EGAC00001000177
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis of 335 primary lung adenocarcinomas and 35 corresponding lymph node metastases from Chinese patients. Altogether 13 si...
We identify abnormal protein and post-translational modification (PTM) pathways, including significantly downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways inextricably linked with can...
ORGANISM(S): Homo Sapiens 
2020-09-18 | PXD021567 |
We identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead...
ORGANISM(S): Homo Sapiens 
2020-09-26 | PXD021700 |
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