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TranscriptomicsTranscriptome analysis of the archaeon Thermoplasma acidophilum cultured under aerobic and anaerobic conditions
Investigation of whole genome gene expression level changes in Thermoplasma acidophilum cultured under aerobic and anaerobic conditions. The analysis are further described in Na Sun, Cuiping Pan, Stephan Nickell, Matthias Mann, Wolfgang Baumeister, and István Nagy, Quantitative proteome and transcri...
ORGANISM(S): Thermoplasma acidophilum DSM 1728 
2011-09-26 | E-GEOD-21956 | biostudies-arrayexpress
TranscriptomicsCharacterization of probiotic Escherichia coli isolates using a novel pangenome microarray
Background: Based on 32 Escherichia coli and Shigella genome sequences, we have developed an E. coli pan-genome microarray. Publicly available genomes were annotated in a consistent manor to define all currently known genes potentially present in the species. The chip design was evaluated by hybridi...
ORGANISM(S): Escherichia coli 
2010-05-26 | E-GEOD-8595 | biostudies-arrayexpress
TranscriptomicsDesign of a Diagnostic Pan-Pathogen Oligonucleotide Microarray including a sub-Array for Detection of Meningitis-Causing Bacterial Pathogens
Meningitis is a complex disease which can be caused by infection with either viral or bacterial pathogens. Viral meningitis is usually a sterile self-limiting disease with a good clinical prognosis, while bacterial meningitis is a potentially more serious disease with a higher mortality rate. Early ...
ORGANISM(S): Listeria monocytogenes 
2011-07-19 | E-GEOD-30794 | biostudies-arrayexpress
TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [gene expression data]
Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-03 | E-GEOD-29704 | biostudies-arrayexpress
MetabolomicsMulti-omics characterization of acquired Olaparib resistance in BRCA1 and BRCA2 mutant breast cancer cell lines
Poly (ADP-ribose) polymerase inhibitors (PARPi) are widely used as targeted therapies against breast cancers with BRCA mutations. However, the development of resistance to PARPi poses a significant challenge for long-term efficacy of these therapies, warranting further understanding of mechanisms of...
2026-05-11 | MTBLS12109 | MetaboLights
UnknownEffective Removal of Pb(II) Ions by Electrospun PAN/Sago Lignin-based Activated Carbon Nanofibers.
Not available
S-EPMC7411989 | biostudies-literature
TranscriptomicsChromatin immunoprecipitation of Arabidopsis 4 day-old light-treated seedlings using anti H3, CT, pan, anti H3K9me2 and IgG antibodies
ChIP was performed using 100 mg of 4 day-old light-treated seedlings. The following antibodies were used: anti H3, CT, pan (Millipore 07-690), anti H3K9me2 (Diagenode pAb-060-050) and IgG (Sigma I50006).
ORGANISM(S): Arabidopsis thaliana 
2009-12-08 | E-MEXP-2480 | biostudies-arrayexpress
UnknownPan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target.
Not available
S-EPMC12923961 | biostudies-literature
GenomicsGenome-wide nucleosome positioning during embryonic stem cell development [ChIP-Seq]
We determined genome-wide nucleosome occupancy in mouse embryonic stem cells and their neural progenitor and embryonic fibroblast counterparts to assess features associated with nucleosome positioning during lineage commitment. Cell type and protein specific binding preferences of transcription fact...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-40951 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of alternative splicing in Caenorhabditis elegans
Alternative splicing (AS) plays a crucial role in the diversification of gene function and regulation. Consequently, the systematic identification and characterization of temporally regulated splice variants is of critical importance to understanding animal development. We have used high-throughput ...
ORGANISM(S): Caenorhabditis elegans 
2010-12-14 | E-GEOD-25927 | biostudies-arrayexpress
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