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MetabolomicsHorizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness

Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread among bacterial isolates and are important genetic determinants of competitive fitness within a given habitat. Staphylococci produce a tremendous diversity of compounds, and the corresponding BGCs are frequen...

2022-11-09 | MTBLS5196 | MetaboLights
UnknownRSV reemergence in Argentina since the SARS-CoV-2 pandemic.
Not available
S-EPMC8906024 | biostudies-literature
TranscriptomicsRNA-seq and genome-wide CRISPRi and Tn-seq analyses of BVL3572S-treated Mycobacterium tuberculosis H37Rv
(i) RNA-seq of M. tuberculosis H37Rv cultures grown in the presence of BVL3572S for 6 h compared to untreated controls. (ii) Genome-wide M. tuberculosis H37Rv CRISPRi libraries were grown in the presence of ATc for 5 days prior to drug exposure. Cultures were treated with sub-MIC BVL3572S concentra...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2026-04-20 | E-MTAB-16773 | biostudies-arrayexpress
ProteomicsA systematic and scalable approach for dissecting the molecular 2 mechanisms of transcriptional regulation in bacteria
Gene regulation is one of the most ubiquitous processes in biology. And yet, while the catalogue of 15 bacterial genomes continues to expand rapidly, we remain ignorant about how almost all of the genes in 16 these genomes are regulated. Characterizing the molecular mechanisms by which regulatory se...
ORGANISM(S): Escherichia Coli 
2018-04-13 | PXD007892 | JPOST Repository
GenomicsWhole genome sequencing of spontaneous resistant mutants of Mycobacterium tuberculosis H37Rv selectec in the presence of BVL3572S and amino acids
M. tuberculosis H37Rv cultures were exposed to BVL3572S in the absence or presence of L-histidine or L-alanine for at least 4 weeks. Individual colonies were picked and their genomic DNA extracted, indexed, and sequenced.
ORGANISM(S): Mycobacterium tuberculosis 
2026-06-03 | E-MTAB-17255 | biostudies-arrayexpress
TranscriptomicsSystematic analysis of time resolved transcriptional signature of the cross-talk between HGF and IL-6 refines the role of Cxcl10 in hepatocyte proliferation control
Liver regeneration is characterized by a scheduled sequence of inner and intra-cellular signaling events. It starts with an initial inflammatory phase, followed by a period of rapidly proliferating hepatocytes and stopping abruptly when the liver mass is restored. The cytokines hepatocellular growth...
ORGANISM(S): Mus musculus 
2016-06-01 | E-GEOD-69928 | biostudies-arrayexpress
Genomicsicgc-liri-jp_release16 - samples
RIKEN collection WGS reads for 100 HCC and matched blood samples from 50 donors submitted to ICGC for release 16
EGAD00001000842 | EGA
Genomicsriken_wgs_mc_im_hcc - samples
RIKEN collection of WGS read of 59 multi-centric liver cancers or intra-haptatic metastasis and matched blood samples from 19 donors.
EGAD00001001643 | EGA
Genomicsena-DATASET-Genentech-13-10-2014-16:40:50:136-199 - samples
Whole genome data (Complete genomics platform) for the study EGAS00001000824
EGAD00001001034 | EGA
Genomicsrnaseq-22hcc - samples
RIKEN collection WGS and RNA-seq reads for 66 HBV-associated HCC and matched blood or liver samples from 22 donors.
EGAD00001001035 | EGA
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