Sort   by:  
 Page size 
UnknownNetwork-based pharmacology and experimental validation to explore the mechanism of action of the Jiawei Pentongling formula for the treatment of endometriosis-related pain.
Not available
S-EPMC11462540 | biostudies-literature
ProteomicsO-GlcNAcylation of Raptor transduces glucose signals to mTORC1
Complex molecular mechanisms ensure cellular homeostasis between nutrient sensing and energy metabolism. Strong evidence from many laboratories supports a role for the hexosamine biosynthetic pathway (HBP) and its end product, UDP-GlcNAc, as important nutrient sensors. Isotopic photocleavable taggin...
ORGANISM(S): Homo sapiens (Human) 
2023-08-03 | PXD039536 | Pride
Mtorc1 Raptor Isoptop Glucose O-glcnac 
ProteomicsQuantitative proteomic Analysis Reveals up-regulation of caveolin-1 inFOXP3-overexpressed human gastric cancer cells
Forkhead box protein 3 (FOXP3) is associated with tumor progression and prognosis in various types of tumor cells. We have recently reported that FOXP3 inhibited proliferation of gastric cancer (GC) cells through activating the apoptotic signaling pathway. In this study, we found that over-expressio...
ORGANISM(S): Homo Sapiens 
2024-08-16 | PXD054940 |
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
Sort   by:  
 Page size