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GenomicsMeis IBA ChIP-seq
Chromatin immunoprecipitation using pan-Meis antibodies in first branchial arch cells from E11.5 mouse embryos detected by SOLiD sequencing
ORGANISM(S): Mus musculus 
2015-02-02 | E-MTAB-1631 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis inflorescence apices from long day grown wild type and pan mutant plants in the KB14 AG::GUS reporter background
inflorescence apices of long day grown wt and pan mutant plants in the KB14 AG::GUS reporter background were compared
ORGANISM(S): Arabidopsis thaliana 
2010-12-31 | E-MEXP-1895 | biostudies-arrayexpress
TranscriptomicsTranscriptome Comparison of Cabernet Sauvignon Grape Berries from Two Regions with Distinct Climate
To obtain an interpretation from the view of transcriptome on distinct metabolite accumulation between ecologically different regions in China, next-generation sequencing technology was performed on E-L 31, 35 and 38 stages of Cabernet Sauvignon grape berries from Changli (CL, eastern) and Gaotai (G...
ORGANISM(S): Vitis vinifera 
2014-11-21 | E-GEOD-63512 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
ProteomicsTEAD inhibitor K-975 enhances KRASG12C inhibitor adagrasib-mediated cancer cell proliferation inhibition via dual cell cycle arrest
Here we investigate the effect of the dual inhibition, in KRASG12C mutated NSCLC cells, using the KRASG12Ci adagrasib (MRTX849) and the pan-TEAD inhibitor (TEADi) K-975. We show that K-975 enhances adagrasib-induced tumor cell growth inhibition in cancer cells. Mechanistically, we detect a downregul...
ORGANISM(S): Homo Sapiens (human) 
2023-05-12 | PXD039726 | JPOST Repository
UnknownTGF-β1 is associated with deficits in cognition and cerebral cortical thickness in first-episode schizophrenia.
Not available
S-EPMC9259382 | biostudies-literature
TranscriptomicsTranscription profiling of chicken histone H1 null mutant cells
In chicken DT40 cells, there are six linker histone H1 variants and 12 of coding genes. We have previously reported of 11 out of 12 H1 knock out DT40 cells (Takami et al., Genes to Cell 1997 [PMID:9491804]) but complete H1 null DT40 cells could not established, so far. We identified one of the H1 va...
ORGANISM(S): Gallus gallus 
2008-11-04 | E-GEOD-8483 | biostudies-arrayexpress
TranscriptomicsA DNA polymerase ? accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast
Specialized chromatin exists at centromeres and must be precisely transmitted during DNA replication. The mechanisms involved in the propagation of these structures remain elusive. Fission yeast centromeres are composed of two chromatin domains: the central CENP-ACnp1 kinetochore domain and flanking...
ORGANISM(S): Schizosaccharomyces pombe 
2008-07-22 | E-GEOD-11102 | biostudies-arrayexpress
ProteomicsIdentification TCF7L2-L, tcf7l2-S and IgG COIP proteins by LC-MS
Identification of binding protein of TCF7L2-L by LC/MS
ORGANISM(S): Homo sapiens (Human) 
2025-01-13 | PXD048102 | Pride
Coip proteins 
GenomicsX-chromosome dynamics revealed by the RNA interactome and chromosomal binding of CTCF
CTCF is a master regulator that plays a role in genome architecture and gene expression. A key aspect of CTCF’s mechanism involves bringing together distant genetic elements for intra- and inter-chromosomal interactions. Evidence from epigenetic processes, such as X-chromosome inactivation (XCI), su...
ORGANISM(S): Mus musculus 
2015-01-09 | E-GEOD-58242 | biostudies-arrayexpress
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