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MetabolomicsMetabolomics dataset of PPAR-pan treated rat liver (eicosanoid assay)

This article contains mass spectrometry (MS) data investigating small molecule changes as an effect of a triple peroxisome proliferator-activated receptor (PPAR-pan) agonist GW625019 in the liver as described in the manuscript “PPAR-pan Activation Induces Hepatic Oxidative Stress and Lipidomic Re...

2016-05-13 | MTBLS278 | MetaboLights
MetabolomicsMetabolomics dataset of PPAR-pan treated rat liver (acyl-carnitine and aqueous metabolite assays)

This article contains mass spectrometry (MS) data investigating small molecule changes as an effect of a triple peroxisome proliferator-activated receptor (PPAR-pan) agonist GW625019 in the liver as described in the manuscript “PPAR-pan Activation Induces Hepatic Oxidative Stress and Lipidomic Re...

2016-05-13 | MTBLS303 | MetaboLights
ProteomicsPlasma proteome profiling reveals the therapeutic effects of the PPAR pan-agonist chiglitazar on insulin sensitivity, lipid metabolism, and inflammation in type 2 diabetes
Chiglitazar is a novel peroxisome proliferator-activated receptor (PPAR) pan-agonist, which passed phase III clinical trials and was newly approved in China for use as an adjunct to diet and exercise in glycemic control in adult patients with Type 2 Diabetes (T2D). To explore the circulating protein...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD039827 | Pride
Human Chiglitazar Dia-ms Diabetes Plasma 
UnknownPan PPAR agonist stimulation of induced MSCs produces extracellular vesicles with enhanced renoprotective effect for acute kidney injury.
Not available
S-EPMC10763307 | biostudies-literature
UnknownPPAR Pan Agonist MHY2013 Alleviates Renal Fibrosis in a Mouse Model by Reducing Fibroblast Activation and Epithelial Inflammation
Not available
S-EPMC10002481 | biostudies-literature
UnknownIn Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist.
Not available
S-EPMC3486420 | biostudies-literature
UnknownIn silico and in vitro investigations reveal pan-PPAR agonist activity and anti-NAFLD efficacy of polydatin by modulating hepatic lipid-energy metabolism.
Not available
S-EPMC12290051 | biostudies-literature
UnknownPhysiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013).
Not available
S-EPMC5370010 | biostudies-literature
UnknownThe pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis.
Not available
S-EPMC11087475 | biostudies-literature
UnknownNovel PPAR pan agonist, ZBH ameliorates hyperlipidemia and insulin resistance in high fat diet induced hyperlipidemic hamster.
Not available
S-EPMC3997506 | biostudies-literature
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