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ProteomicsInterspecific and Intraspecific Variation in Venom Proteomics, Composition, and Antivenom Efficacy of Thai Cobras (Naja spp.): Highlighting the Distinct Profile of the Newly Identified Naja fuxi.
Cobras (Naja spp.) account for a significant number of snakebite incidents in Thailand. The monocled cobra (Naja kaouthia) has historically been considered the only non-spitting species, but recent evidence indicates population-level diversification in central and southern regions. Additionally, a n...
ORGANISM(S): Naja sp. Trimeresurus 
2026-04-21 | PXD073641 | Pride
Geographical variation Neutralisation Immunoreactivity Cobra venom proteome Naja fuxi Enzyme assays 
ProteomicsDiscovery of a potent and selective covalent inhibitor and activity-based probe for UCHL1, with anti-fibrotic activity
Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme (DUB) that is very highly expressed in human brain. UCHL1 has been proposed as a potential therapeutic target in neurodegeneration, cancer, and liver and lung fibrosis, however bona fide molecular functions of UCHL1 are yet...
ORGANISM(S): Homo sapiens (Human) 
2020-11-12 | PXD015825 | Pride
Activity based-probe profiling Human Uchl1 Chemical proteomics Deubiquitination 
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