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Human papillomaviruses (HPV) preferentially infect keratinocytes of mucous membranes or skin and cause numerous benign and malignant lesions at different anatomical locations. A number of DNA viruses encode their own miRNAs as well. To date, no studies have been able to validate viral miRNAs in papi...
ORGANISM(S): Homo sapiens 
To identify early processes in carcinogenesis, we used an in vitro model, based on the initiating event in cervical cancer, human papillomavirus (HPV) transformation of keratinocytes. We compared gene expression in primary keratinocytes (K) and HPV16-transformed keratinocytes from early (E) and late...
ORGANISM(S): Homo sapiens 
Oncogene expressing human papillomavirus type 16 (HPV16) is found in a subset of head and neck squamous cell carcinomas (HNSCC). HPV16 drives carcinogenesis by inactivating p53 and pRb with the viral oncoproteins E6 and E7, reflected by a low level of mutations in TP53 and allelic loss at 3p, 9p and...
ORGANISM(S): Homo sapiens 
Human papillomavirus Raw sequence reads
Human papillomavirus isolate:HPV_MGH-TT01 Genome sequencing and assembly
Human papillomavirus genotyping
Human Papillomavirus Raw sequence reads
Human papillomavirus Raw sequence reads
Human papillomavirus Raw sequence reads
The effect of human papillomavirus 16 E5 oncogene on cellular gene expression in human epithelial cells was studied. Alterations in cellular gene expression due to human papillomavirus type 16 E5 oncogene were studied in triplicate microarray screens. Epithelial cells where E5 expression was induced...
ORGANISM(S): Homo sapiens 
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