Sort   by:  
 Page size 
TranscriptomicsDPN and Tamoxifen treatments of parathyroid adenoma cells
Stimulation of estrogen receptor beta in PHPT, genetic changes after 24 and 48h of treatments vs. Control Treatment of parathyroid adenomas (4 patients, 4 adenomas) with DPN 24h (4 samples), DPN 48h (4 samples), OHT 24h (4 samples), OHT 48h (4 samples), control 24h (3 samples), control 48h (4 sample...
ORGANISM(S): Homo sapiens 
2012-09-19 | E-GEOD-37211 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary osteoblastic cells after intermittent of continuous treatment with parathyroid hormone to investigate the role of beta-arrestin2
Role of beta-arrestin2 in response to intermittent or continuous parathyroid hormone (PTH) treatment.
ORGANISM(S): Mus musculus 
2009-07-20 | E-TABM-624 | biostudies-arrayexpress
TranscriptomicsGenetic characterization of large parathyroid adenomas
We genetically characterized parathyroid adenomas with large glandular weights, for which independent observations suggest pronounced clinical manifestations. Large parathyroid adenomas (LPTAs) were defined as the 5% largest sporadic parathyroid adenomas identified among the 590 cases operated on in...
ORGANISM(S): Homo sapiens 
2012-05-08 | E-GEOD-36511 | biostudies-arrayexpress
TranscriptomicsProlactin stimulation of parathyroid adenomas
Primary hyperparathyroidism is a common endocrine disorder frequently affecting postmenopausal women. In this study we have investigated expression of the prolactin receptor (PRLr) in a panel of 37 sporadic parathyroid tumours, as well as functionality in vitro in cultured parathyroid tumour cells. ...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-32387 | biostudies-arrayexpress
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine, plasma and liver NMR assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non-relevant doses or in combination with other r...
2018-05-01 | MTBLS602 | MetaboLights
TranscriptomicsTranscription profiling of human organ culture of hyperparathyroidism reveals that phosphate stimulates parathyroid cell proliferation and pth release
The pathogenesis of primary hyperparathyroidism (I-HPT) and secondary hyperparathyroidism (II-PTH) remains to be elucidated. To characterize their pathophysiology, we investigated the effects of calcium and phosphate on cell proliferation and PTH release in an organ culture of parathyroid tissues. D...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-11423 | biostudies-arrayexpress
TranscriptomicsTranscriptional profile by mRNA microarrays of cervical thymus, thoracic thymus and parathyroid from Foxn1-GFP; Pth-Cre; R26dTomato transgenic mice
Whole mouse genome microarrays from Agilent were used to determine expression profile of whole organ cervical thymus, thoracic thymus and parathyroid from Foxn1-GFP; Pth-Cre; R26dTomato transgenic mice.
ORGANISM(S): Mus musculus 
2015-07-31 | E-MTAB-3751 | biostudies-arrayexpress
GenomicsParathyroid hormone exacerbates pulmonary hypertension through hypoxia-induced parathyroid hormone receptor upregulation.
Parathyroid hormone exacerbates pulmonary hypertension through hypoxia-induced parathyroid hormone receptor upregulation.
PRJNA1025021 | ENA
TranscriptomicsMolecular patterns of diffuse and nodular parathyroid hyperplasia in long-term hemodialysis
Secondary hyperparathyroidism is well known complication manifested in end-stage renal disease (ESRD). Both nodular and diffuse parathyreoid hyperplasia occur in ESRD patients. Distinct molecular mechanisms involved in parathyreoid hyperplasia remain poorly understood. Microarray screening proved ho...
ORGANISM(S): Homo sapiens 
2015-12-12 | E-GEOD-75886 | biostudies-arrayexpress
TranscriptomicsExpression profiles of parathyroid glands from healthy pigs challenged by fetal and postnatal dietary interventions
Calcium (Ca) and phosphorus (P) are essential micronutrients that are linked to a wide set of biological processes. A deeper understanding of the molecular mechanisms of Ca- and P-utilization in sows and their offspring could help to reduce the environmental impact. Parathyroid glands play an import...
ORGANISM(S): Sus scrofa 
2024-11-30 | E-MTAB-9768 | biostudies-arrayexpress
Sort   by:  
 Page size