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GBS data of wild emmer and durum wheat
In malaria parasites, evolution of parasitism has been linked to functional optimisation. Despite this optimisation, most members of a calcium-dependent protein kinase (CDPK) family show genetic redundancy during erythrocytic proliferation. To identify relationships between phospho-signalling pathwa...
ORGANISM(S): Plasmodium berghei ANKA 
2018-09-17 | PXD011096 | Pride
Toxoplasma gondii is able to establish a life-long chronic infection in human and animals. Host cell entry and egress from infected cells are two key steps in the lytic cycle of this obligate intracellular parasite that ensures its survival and dissemination. Egress is a temporally orchestrated proc...
ORGANISM(S): Toxoplasma gondii 
2018-11-14 | PXD011692 | Pride
One of the key innovations of the flowering plants is their female reproductive organ, the carpel. Here we show that a mechanism controlling carpel margin development in the model flowering plant Arabidopsis thaliana was recruited from light-regulated processes. This recruitment followed the loss fr...
ORGANISM(S): Arabidopsis thaliana 
A cell line (MFD-1) was derived from a 55-year old male with oesophageal adenocarcinoma. Using different sources of genetic material from normal and tumour tissue surgically resected, peripheral blood and the derived cell line a high concordance of genotypes calls across the whole genome confirms MF...
ORGANISM(S): Homo sapiens 
Cell-cycle transitions are generally triggered by variations in the activity of cyclin-dependent kinases (CDKs) bound to cyclins. Malaria parasites express ancestral CDKs and cyclins, whose functions and interdependency remain elusive. Here, we show that the unique Plasmodium berghei CDK-related kin...
ORGANISM(S): Plasmodium berghei ANKA 
2020-02-18 | PXD017283 | Pride
Hepcidin is demonstrated to be the key iron regulatory hormone, produced by the liver. Here we show an unexpected role of hepcidin as a master initiator of the local and systemic inflammatory response. We found that hepcidin was highly expressed in the colon of two major idiopathic inflammatory bowe...
ORGANISM(S): Mus musculus 
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