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TranscriptomicsRAW264.7 cells were treated with KDO, IFN beta and 8Br
RAW 264.7 cells were stimulated with KDO (100 ng/ml), IFN-β (300 pM) and/or 8-Br 100 μM. These ligands were applied individually or in combination with KDO for 60 min and 120 min. Total RNA was extracted using TriPure (Roche) following its protocol. Keywords: designed RAW 264.7 cells were stimulat...
ORGANISM(S): Mus musculus 
2008-06-28 | E-GEOD-11449 | biostudies-arrayexpress
ProteomicsProteomics based analysis for associated PD-L1 in macrophage stimulated with extracellular adenosine signaling
We performed proteomics analysis to discover effector proteins for the post-transcriptional regulation of PD-L1 onhuman macrophages stimulated by adenosine signal.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD024512 | Pride
Macrophage adenosin 
UnknownAssociation Between Income Disparities and Risk of Chronic Kidney Disease: A Nationwide Cohort Study of Seven Million Adults in Korea.
Not available
S-EPMC7224965 | biostudies-literature
UnknownOptimal Nozzle Position and Patient's Posture to Enhance Drug Delivery into the Peritoneum during Rotational Intraperitoneal Pressurized Aerosol Chemotherapy in a Swine Model.
Not available
S-EPMC9695236 | biostudies-literature
UnknownDiscovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
Not available
S-EPMC4948015 | biostudies-literature
ProteomicsHypoxia increases the methylated histones to prevent histone clipping and redistribution of heterochromatin during Raf-induced senescence.
Hypoxia in stem cell niches and inner core of solid tumors contributes to cellular senescence and differentiation inhibition. It directly increases histone methylationby inhibiting the activities of O2-and α-ketoglutarate (α-KG)-dependent histone lysine demethylases. This study is the first to demon...
ORGANISM(S): Homo sapiens (Human) 
2024-11-27 | PXD033971 | Pride
Human Top-down Histone Proteomics 
ProteomicsProteomics analysis between T cell lysate and T cell microvilli-derived particles
Although T cell activation is closely linked to internalization of the T cell antigen receptor (TCR), relatively few studies have examined the release of TCRs via shedding of T cell microvilli following physical interaction with cognate antigen-presenting cells. In this study, we investigated the ph...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-09 | PXD041442 | Pride
Extracellular vesicle Proteomics T cell microvilli 
ProteomicsEpigenetic resetting in the Parkinson's disease entail histone modification remodeling.
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons (DN) in the substantia nigra and disrupted cellular maintenance. Here, we demonstrate that NDST3-mediated epigenetic reprogramming halts neuronal degeneration and restores motor...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD067971 | Pride
Human Tmt Parkinson's Organoid Lc-ms/ms 
ProteomicsMycobacterium tuberculosis extracellular vesicle proteome
Tuberculosis is a common infectious disease mostly caused by Mycobacterium tuberculosis. M. tuberculosis have been shown to release extracellular vesicles (EVs) containing immunologically active molecules. However, only limited number of proteins has been identified in M. tuberculosis EVs. We presen...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2015-07-30 | PXD001160 | Pride
Exosomes Mycobacterium tuberculosis Extracellular vesicles Outer membrane vesicles Bacteria 
ProteomicsUbiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function
Eph receptor tyrosine kinases participate in a variety of normal and pathogenic processes during development and throughout adulthood. This versatility is likely facilitated by the ability of Eph receptors to signal through diverse cellular signalling pathways: primarily by controlling cytoskeletal ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-29 | PXD041786 | Pride
Ap-ms Ephb2 Lc-ms/ms 
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