Sort   by:  
 Page size 
Cardiac-specific PPARalpha transgenic (Tg-PPARalpha) mice show mild cardiac hypertrophy and systolic dysfunction. The failing heart phenotypes observed in Tg-PPARalpha are exacerbated by crossing with cardiac-specific Sirt1 transgenic (Tg-Sirt1) mice, whereas Tg-Sirt1 mice themselves do not show any...
ORGANISM(S): Mus musculus 
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here, ...
2021-03-05 | MTBLS2159 | MetaboLights
LARS undergoes structural changes in response to amino acid stimulation and translocates to lysosome, exhibiting non-canonical functions such as mTORC1 activation instead of its canonical function of tRNA amino-acylation. This study investigates which post-translational modifications (PTMs) of LARS ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD066801 | Pride
Sort   by:  
 Page size