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ProteomicsPlasma EVs-Derived Complement Proteins as Biomarkers of Sarcopenia Progression in Longitudinal Cohorts
Sarcopenia is characterized by progressive loss of muscle mass, strength, and physical performance, yet current diagnostic tools are limited for practical and longitudinal monitoring. To explore alternative biomarkers, we performed quantitative proteomic profiling of plasma-derived extracellular ves...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD073288 | Pride
extracellular vesicles Sarcopenia Biomarkers Aging Complement proteins 
ProteomicsnextPP for chromosome-based proteomic research using neXtProt and GENCODE databases
In this study, we introduce a streamlined pipeline using customized and concatenated GENCODE and neXtProt databases with controlled false discovery rate (FDR) for finding GENCODE ASVs and missing proteins while mapping onto single amino acid variants (SAAVs) from Hippocampal dataset.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-07-25 | MSV000081385 | MassIVE
ProteomicsSynphilin-1 upregulates RBL2 expression and causes a G0/G1 phase cell cycle arrest in the neurons
Synphilin-1, a major component of Lewy bodies in the brain of Parkinsons disease (PD) patients, is a cytoplasmic protein that interacts with alpha-synuclein and is suggested to have cytoprotective effects in the neuronal cells. alpha-Synuclein overexpression induced re-entry of the neuronal cells in...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2022-07-20 | MSV000089926 | MassIVE
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.

Purpose

Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in ad...
S-EPMC7880913 | biostudies-literature
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