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UnknownImportance of family history of diabetes in computing a diabetes risk score in Korean prediabetic population.
Prediabetic subjects represent a vulnerable population, requiring special care to reduce the risk of diabetes onset. We developed and validated a diabetes risk score for prediabetic subjects using the Korea National Diabetes Program (KNDP) cohort. Subjects included in the multicenter and prospective...
S-EPMC6206127 | biostudies-literature
UnknownHypoglycemia and Medical Expenses in Patients with Type 2 Diabetes Mellitus: An Analysis Based on the Korea National Diabetes Program Cohort.

Background and aims

Hypoglycemia is one of the most important adverse events in individuals with type 2 diabetes mellitus (T2DM). However, hypoglycemia-related events are usually overlooked and have been documented less in clinical practice.

Materials and methods

We evaluated the inci...
S-EPMC4758656 | biostudies-literature
UnknownInsulin secretion and insulin resistance in Korean women with gestational diabetes mellitus and impaired glucose tolerance.

Background/aims

The aim was to compare the insulin sensitivity and secretion index of pregnant Korean women with normal glucose tolerance (NGT), gestational impaired glucose tolerance (GIGT; only one abnormal value according to the Carpenter and Coustan criteria), and gestational diabetes me...
S-EPMC3654128 | biostudies-literature
UnknownThe Association of Smoking Status with Diabetic Microvascular Complications in Korean Patients with Type 2 Diabetes.

Purpose

Few studies have investigated the association between smoking and microvascular complications in the Asian population with type 2 diabetes mellitus (T2DM). We aimed to investigate the relationship between smoking status and microvascular complications in Korean patients with T2DM.
S-EPMC11284303 | biostudies-literature
UnknownImpact of diabetes distress on glycemic control and diabetic complications in type 2 diabetes mellitus.
The effect of diabetes distress on glycemic control and its association with diabetes complications is still poorly understood. We aimed to study the clinical features of patients with high diabetes distress, focusing on changes in glycemic control and risk of diabetic complications. From the Korean...
S-EPMC10917807 | biostudies-literature
UnknownFailure of monotherapy in clinical practice in patients with type 2 diabetes: The Korean National Diabetes Program.

Aims/introduction

We investigated the failure of monotherapy in patients with type 2 diabetes mellitus in real practice settings.

Materials and methods

The Korean National Diabetes Program was a prospective, multicenter observational cohort study of type 2 diabetes mellitus patients i...
S-EPMC6123024 | biostudies-literature
UnknownPresence of Carotid Plaque Is Associated with Rapid Renal Function Decline in Patients with Type 2 Diabetes Mellitus and Normal Renal Function.

Background

Recent evidences indicate that early rapid renal function decline is closely associated with the development and progression of diabetic kidney disease. We have investigated the association between carotid atherosclerosis and rapid renal function decline in patients with type 2 di...
S-EPMC6943261 | biostudies-literature
UnknownC1q/TNF-related protein-3 (CTRP-3) and pigment epithelium-derived factor (PEDF) concentrations in patients with type 2 diabetes and metabolic syndrome.
Recent studies have suggested that a novel adipokine, C1q/tumor necrosis factor-related protein-3 (CTRP-3), a paralog of adiponectin, may play an important role in the regulation of glucose metabolism and innate immunity. Pigment epithelium-derived factor (PEDF), a multifunctional protein with antio...
S-EPMC3478553 | biostudies-literature
UnknownTargeting the Hippo pathway in Schwann cells ameliorates peripheral nerve degeneration via a polypharmacological mechanism.
Peripheral neuropathies (PNs) are common diseases in elderly individuals characterized by Schwann cell (SC) dysfunction and irreversible Wallerian degeneration (WD). Although the molecular mechanisms of PN onset and progression have been widely studied, therapeutic opportunities remain limited. In t...
S-EPMC11585884 | biostudies-literature
UnknownImpact of Socioeconomic Status on Health Behaviors, Metabolic Control, and Chronic Complications in Type 2 Diabetes Mellitus.

Background

The aim of the study was to assess the impact of socioeconomic status (SES) on health behaviors, metabolic control, and chronic complications in people with type 2 diabetes mellitus (T2DM) from South Korea, a country with universal health insurance coverage and that has experience...
S-EPMC6202566 | biostudies-literature
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