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MetabolomicsShort-term changes in the serum metabolome after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass

INTRODUCTION: Bariatric surgery is known to be the most effective treatment for weight loss in obese patients and for the rapid remission of obesity-related comorbidities. These short-term improvements result from not only limited digestion or absorption but also dynamic changes ...

2022-03-17 | MTBLS2472 | MetaboLights
ProteomicsIntegrative multi-scale physiological, metabolic, and proteomic reprogramming in tomato under polyethylene microplastic stress
This dataset contains bottom-up, label-free proteomic data from tomato roots exposed to polyethylene microplastics under soil conditions. Tomato plants (Solanum lycopersicum cv. Super Dotaerang) were grown for 48 days in agricultural soil containing 0%, 1%, or 5% (w/w) polyethylene microplastics. Ro...
ORGANISM(S): root Solanum lycopersicum 
2026-10-20 | PXD076181 | Pride
Tomato  solanum lycopersicum  root proteomics  polyethylene microplastics  label-free quantification  abiotic stress  dda  bottom-up proteomics 
GenomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cell (hMeDIP-Seq and MBD-Seq)
DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge about the genome-wide distribution of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) during cellular differentiation remains limited. Using in vitro model system of gra...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38214 | biostudies-arrayexpress
TranscriptomicsDynamic changes of DNA methylome and hydroxymethylome during neural differentiation of hES cells (Methylation BeadChip)
DNA methylation and hydroxymethylation have been implicated in normal development and differentiation, but our knowledge about the genome-wide distribution of 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) during cellular differentiation remains limited. Using in vitro model system of gra...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-38216 | biostudies-arrayexpress
UnknownIntegrative and comparative genomic analysis of lung squamous cell carcinomas in East Asian patients.

Purpose

Lung squamous cell carcinoma (SCC) is the second most prevalent type of lung cancer. Currently, no targeted therapeutics are approved for treatment of this cancer, largely because of a lack of systematic understanding of the molecular pathogenesis of the disease. To identify therapeu...
S-EPMC4062710 | biostudies-literature
MetabolomicsSnail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
MetabolomicsGNPS - MassIVE data submission of Taraxacum MSe data
LC-MSe data of 13 Taraxacum species (whole plant body) extracts for analyzing their chemical diversity, including 8 QC samples (mixture of all the samples in same conc.)
ORGANISM(S): Taraxacum Platycarpum (ncbitaxon:170727) Taraxacum Officinale (ncbitaxon:50225) Taraxacum Ohwianum Taraxacum Coreanum (ncbitaxon:1041103) Taraxacum Mongolicum (ncbitaxon:90037) 
2020-02-06 | MSV000084931 | GNPS
UnknownRobust estimation of bacterial cell count from optical density.
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-...
S-EPMC7499192 | biostudies-literature
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