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ProteomicsA genetically-encoded crosslinker screen identifies SERBP1 as a PKC substrate influencing translation and cell division
The PKC-regulated genome protective pathway provides transformed cells a failsafe to successfully complete mitosis. Despite the necessary role for Aurora B in this programme, it is unclear whether its requirement is sufficient or if other PKC cell cycle targets are involved. To address this, we deve...
ORGANISM(S): Homo sapiens (Human) 
2021-12-09 | PXD029091 | Pride
Human 
ProteomicsCoordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention
The N371 site on PKCe was mutated to TAG in an expression plasmid. This was co-transfected in a 1:1 ratio with a plasmid that encodes both an aaRS optimised to recognise AbK, and the tRNAPyl which recognises the UAG codon.
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD025959 | Pride
14-3-3 pkce Mass spectrometry Phosphorylation 
UnknownTransitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
Not available
S-EPMC5264208 | biostudies-literature
UnknownTemporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Not available
S-EPMC11221519 | biostudies-literature
UnknownWAO consensus on DEfinition of Food Allergy SEverity (DEFASE).
Not available
S-EPMC9996094 | biostudies-literature
UnknownPrognostic gene expression signature for high-grade serous ovarian cancer.
Not available
S-EPMC7484370 | biostudies-literature
UnknownTailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer.
Not available
S-EPMC6193457 | biostudies-literature
UnknownShared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.
Not available
S-EPMC7429266 | biostudies-literature
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
GenomicsImputation analysis file
This data set includes the following summary level data file used for the imputation data: imputation.sv.assoc.txt: results from single variant association analysis in imputed samples
EGAD00010001184 | EGA
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