We sought to determine whether the vault complex component Poly (ADP-ribose) Polymerase 4 (PARP4) would impact the identity or relative enrichment of proteins that interacted with the vault. We conducted co-immunoprecipitation (co-IP) experiments targeting the human major vault protein (MVP) using a...
Background: The identification of cancer driver genes from sequencing data has been crucial in deepening our understanding of tumor biology and expanding targeted therapy options. However, apart from the most commonly altered genes, the mechanisms underlying the contribution of other mutations to c...
