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MetabolomicsSuboxic DOM is bioavailable to surface prokaryotes in a simulated overturn of an oxygen minimum zone, Devil’s Hole, Bermuda
Oxygen minimum zones (OMZs) are expanding due to increased sea surface temperatures, subsequent increased oxygen demand through respiration, reduced oxygen solubility, and thermal stratification driven in part by anthropogenic climate change. Devil's Hole, Bermuda is a model ecosystem to study OMZ m...
2024-02-27 | MTBLS8122 | MetaboLights
TranscriptomicsInduction of Senescence in Diterpene Ester-Treated Melanoma Cells via PKC-dependent Hyperactivation of the MAPK Pathway
The diterpene ester PEP005 is a novel anticancer agent that activates PKC and cures subcutaneous murine melanoma by topical application. We now describe the in vitro cytostatic effects of PEP005 and the diterpene ester TPA, observed in 20% of human melanoma cell lines. Primary cultures of normal h...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-3484 | biostudies-arrayexpress
UnknownThe VetMAX™ M. tuberculosis complex PCR kit detects MTBC DNA in antemortem and postmortem samples from white rhinoceros (Ceratotherium simum), African elephants (Loxodonta africana) and African buffaloes (Syncerus caffer).
Not available
S-EPMC7325085 | biostudies-literature
ProteomicsDissecting the secretory pathway with electrophoresis reveals intra-Golgi trafficking pathways and enables compilation of sub-Golgi and sub-ER proteomes.
The Golgi is the hub of the eukaryotic secretory pathway, trafficking proteins and lipids, as well as synthesizing complex sugars. Different biosynthetic reactions are associated with different compartments of its complex architecture. Although pre- and post-Golgi trafficking has been much studied...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-09-11 | PXD004596 | Pride
Arabidopsis Free flow electrophoresis Proteomics Trans-membrane span Secretory pathway Polysaccharide Endoplasmic reticulum Trafficking Golgi Cisternae Immunogold 
TranscriptomicsExpression data from Epithelial colon cancer cells treated with TGF-beta
Most available CRC cell lines have lost their TGF-beta response through the acquisition of mutations either in TGF-beta type II receptor (TGFBR2) or the intracellular mediator SMAD4 (Reviewed in Markowitz et al. 2002). To study the effect of TGF-beta in CRC epithelial cells, we restored wild-type TG...
ORGANISM(S): Homo sapiens 
2014-09-08 | E-GEOD-59771 | biostudies-arrayexpress
UnknownPast and future trends of Egypt's water consumption and its sources.
Not available
S-EPMC8302683 | biostudies-literature
ProteomicsAnalysing alpha4 and alpha9 integrin complex partners
Adhesion of basal keratinocytes to the underlying extracellular matrix (ECM) plays a key role in the control of skin homeostasis and response to injury. Integrin receptors indirectly link the ECM to the cell cytoskeleton through large protein complexes called focal adhesions (FA). FA also function a...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027944 | Pride
Human Keratinocytes Lc-ms/ms 
UnknownSeed set variation in wild Clarkia populations: teasing apart the effects of seasonal resource depletion, pollen quality, and pollen quantity.
Not available
S-EPMC5058524 | biostudies-literature
ProteomicsProteomic analysis of separated Golgi cisternae gives insights into secretory pathway organization Proteomic analysis of separated Golgi cisternae gives insights into secretory pathway organization
The Golgi apparatus is the hub of the secretory pathway, trafficking proteins and lipids and synthesizing complex glycans. The spatial distribution of resident proteins across individual Golgi cisternae is functionally essential for complex molecule biosynthesis. However, the inability to-date to se...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-09-11 | PXD009978 | Pride
Proteomic analysis of separated golgi cisternae gives insights into secretory pathway organization 
UnknownOn the Environmental Determinants of COVID-19 Seasonality.
Not available
S-EPMC8166213 | biostudies-literature
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