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TranscriptomicsNew insight into a host-pathogen interaction unveiled by transcriptomics response of the global insect pest Plutella xylostella to a fungal pathogen
A genomic insight into how an insect pest responds to the infection of a fungal insect pathogen, such as Beauveria bassiana, is critical for alternative strategy of insect pest contol based on fungal insecticides but has not been well probed. Here we constructed three pairs of digital expression lib...
ORGANISM(S): Plutella xylostella 
2016-04-06 | E-GEOD-72383 | biostudies-arrayexpress
ProteomicsOrientia tsutsugamushi proteome profile host context
Emerging and neglected pathogens pose challenges as their biology is frequently poorly understood, and genetic tools often do not exist to manipulate them. Organism agnostic sequencing technologies offer a promising approach to understand the molecular processes underlying these diseases. Here we ap...
ORGANISM(S): Cellular Organisms 
2020-06-05 | PXD017956 | JPOST Repository
TranscriptomicsThe miR-126/VEGFR2 axis controls the innate response to pathogen-associated nucleic acids
microRNA-126 is a microRNA predominately expressed by endothelial cells and controls angiogenesis. Unexpectedly, we found that mice deficient in miR-126 have a major impairment in their innate response to pathogen-associated nucleic acids, as well as HIV, which results in more widespread cell infect...
ORGANISM(S): Mus musculus 
2013-11-24 | E-GEOD-51255 | biostudies-arrayexpress
ProteomicsA cullin-RING ubiquitin ligase promotes thermotolerance as part of the Intracellular Pathogen Response in C. elegans.
Intracellular pathogen infection leads to proteotoxic stress in host organisms. Previously we described a physiological program in the nematode C. elegans called the Intracellular Pathogen Response (IPR), which promotes resistance to proteotoxic stress and appears to be distinct from canonical prote...
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2020-02-07 | MSV000084936 | MassIVE
GenomicsThe transcriptomic landscape of the photoperiodic stress response in Arabidopsis thaliana resembles the response to pathogen infection
The transcriptomic landscape of the photoperiodic stress response in Arabidopsis thaliana resembles the response to pathogen infection
PRJNA727531 | ENA
ProteomicsProteomic response of the early divergent liverwort Marchantia polymorpha during infection with the oomycete pathogen Phytophthora palmivora
Here, we define the proteomic response of the early divergent liverwort Marchantia polymorpha during infection with the oomycete pathogen Phytophthora palmivora. We sampled whole liverwort thalli that were mock-inoculated (water) or infected with P. palmivora zoospores at 4 and 8 days post inoculati...
ORGANISM(S): Marchantia polymorpha subsp. ruderalis 
2019-06-24 | PXD012076 | Pride
Pathogen-response Marchantia polymorpha Plant immunity Lc-ms/ms 
GenomicsPathogen-specific innate immune response patterns are distinctly affected by genetic diversity
Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity
PRJNA736947 | ENA
GenomicsTranscriptional profiling specifies the pathogen-specific human host response to infectious keratitis
Transcriptional profiling specifies the pathogen-specific human host response to infectious keratitis
PRJNA1009389 | ENA
TranscriptomicsConserved nutrient sensor O-GlcNAc transferase is integral to the C. elegans pathogen-specific immune response
Discriminating pathogenic bacteria from energy-harvesting commensals is key to host immunity. Using mutants defective in the enzymes of O-linked N-acetylglucosamine (O-GlcNAc) cycling, we examined the role of this nutrient-sensing pathway in the Caenorhabidits elegans innate immune response. Using w...
ORGANISM(S): Caenorhabditis elegans 
2015-05-01 | E-GEOD-53732 | biostudies-arrayexpress
GenomicsEscalation in the host-pathogen arms race: a host resistance response corresponds to a heightened bacterial virulence response
Escalation in the host-pathogen arms race: a host resistance response corresponds to a heightened bacterial virulence response
PRJNA595608 | ENA
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