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MetabolomicsThe murine lung microbiome is dysbalanced by the human pathogenic fungus Aspergillus fumigatus resulting in enrichment of anaerobic bacteria
Here, we report significant changes in the composition of the lung microbiome and metabolome of mice under immune suppression, infection of immunosuppressed mice with virulent and avirulent strains of the clinically important human-pathogenic fungus Aspergillus fumigatus, and treatment with the clin...
2025-07-04 | MTBLS12262 | MetaboLights
MetabolomicsMetabolomic and Proteomic Profiling of the Antimicrobial Potentials from Lactobacillus johnsonii KD1 Cell-Free Supernatant against Foodborne Pathogenic Bacteria

This study characterized functions and metabolic profiles of cell-free supernatants (CFS) from Lactobacillus johnsonii KD1 against three foodborne pathogens: the Gram-negative bacteria Vibrio parahaemolyticus 3HP and Salmonella enterica serovar ...

2026-09-24 | MTBLS14550 | MetaboLights
MetabolomicsExtracellular ATP is an environmental cue in bacteria

In animals and plants extracellular ATP (eATP) functions as signal and regulates the immune response. During inflammation intestinal bacteria are exposed to elevated eATP originating from the mucosa. However, whether bacteria respond to eATP is unclear. Here we show that non-pathogenic Escherichi...

2025-08-28 | MTBLS12905 | MetaboLights
MetabolomicsF1Fo-ATP synthase subunit determines lethal pathogenic fungi infection
Fungal infections, especially candidiasis and aspergillosis, claim an unacceptably high fatality rate. The energy ATP that is necessary for fungal cell growth and function is synthesized mainly through oxidative phosphorylation, with the key enzyme being F1Fo-ATP synthase. But it remains unknown how...
2021-10-08 | MTBLS3332 | MetaboLights
TranscriptomicsTransfer of Non-coding DNA Drives Regulatory Rewiring in Bacteria
The rapid pace of evolution in bacteria is widely attributed to the promiscuous horizontal transfer and recombination of protein-coding genes. However, it is not known whether the same forces also drive the evolution of non-coding regulatory regions. Here we demonstrate that regulatory region can M-...
ORGANISM(S): Escherichia coli CFT073 
2014-11-04 | E-GEOD-59468 | biostudies-arrayexpress
GenomicsClinical pathogenic bacteria detection
Clinical pathogenic bacteria detection
PRJEB46246 | ENA
TranscriptomicsComparative transcriptomics of pathogenic and non-pathogenic Listeria species
Listeria monocytogenes is a human, food-borne pathogen. Genomic comparisons between L. monocytogenes and Listeria innocua, a closely related non-pathogenic species, were pivotal in the identification of protein coding genes essential for virulence. However, no comprehensive comparison has focused on...
ORGANISM(S): Listeria monocytogenes EGD-e 
2012-05-01 | E-GEOD-36060 | biostudies-arrayexpress
Genomicspathogenic bacteria source track
pathogenic bacteria source track Metagenome
PRJNA1238032 | ENA
TranscriptomicsRNA-Sequencing analysis of the Drosophila transcriptomic response to infection by entomopathogenic nematodes and their mutualistic bacteria
We report the application of next generation RNA sequencing to analyze the transcriptional response of Drosophila adult flies to infection by the insect pathogenic nematodes Heterorhabditis bacteriophora and their mutualistic bacteria Photorhabdus luminescens, either separately or together. We find ...
ORGANISM(S): Drosophila melanogaster 
2015-09-12 | E-GEOD-61466 | biostudies-arrayexpress
GenomicsPathogenic bacteria
Comparative analysis of benchmarking high molecular weight DNA isolation kits for long-read sequencing of pathogenic bacteria
PRJNA909850 | ENA
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