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MetabolomicsA general non-self response as part of plant immunity
Plants, like other multicellular lifeforms, are colonized by microorganisms. How plants respond to their microbiota is currently not well understood. We used a phylogenetically diverse set of 39 endogenous bacterial strains from Arabidopsis thaliana leaves to assess host transcriptional and metaboli...
2021-09-13 | MTBLS2522 | MetaboLights
TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | E-GEOD-52340 | biostudies-arrayexpress
TranscriptomicsPustular psoriasis: molecular pathways and effects of spesolimab in generalized pustular psoriasis
pre- and post spesolimab treatment gene expression analysis of blood as well as skin biopsy samples.
ORGANISM(S): Homo sapiens 
2023-06-04 | E-MTAB-11144 | biostudies-arrayexpress
UnknownClinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastases.
Not available
S-EPMC4451171 | biostudies-literature
TranscriptomicsRNA-seq of mice genital ridges from males and females at embryonic days E11 and E12
The aim of the study was to identify differentially expressed genes, isoforms and AS modifications accompanying Gonadal Sex Determination in mice. We performed a Rna-Seq analysis of XX and XY gonads during sex determination on embryonic days 11 (E11) and 12 (E12). RNA-seq libraries were prepared fro...
ORGANISM(S): Mus musculus 
2019-02-21 | E-MTAB-7656 | biostudies-arrayexpress
ProteomicsEvaluation of iTRAQ and SWATH-MS for the quantification of proteins associated with insulin resistance in human duodenal biopsy samples
Insulin resistance (IR) is associated with increased production of triglyceride-rich lipoproteins of intestinal origin. In order to assess whether insulin resistance affects the proteins involved in lipid metabolism, we used two mass spectrometry based quantitative proteomics techniques to compare t...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080194 | MassIVE
UnknownInfectious Disease Underreporting Is Predicted by Country-Level Preparedness, Politics, and Pathogen Severity.
Not available
S-EPMC10818036 | biostudies-literature
TranscriptomicsRNA-Seq experiment to identify genes regulated by ATF4
Activating Transcription Factor 4 (ATF4) is a transcription factor induced by the integrated stress response (ISR). This experiment is a genome-wide profiling of ATF4-dependent RNA expression in human HAP-1 cells. HAP-1 is a near-haploid human cell line that was derived from KBM-7 cells isolated fro...
ORGANISM(S): Homo sapiens 
2015-08-28 | E-GEOD-69308 | biostudies-arrayexpress
GenomicsGenome-wide analysis of ATF4 binding in histidinol-treated cells
Activating Transcription Factor 4 (ATF4) is a transcription factor induced by the integrated stress response (ISR). This experiment is a genome-wide occupancy profiling of ATF4 in human HAP1 cells. HAP1 is a near-haploid human cell line that was derived from KBM-7 cells isolated from a patient with ...
ORGANISM(S): Homo sapiens 
2015-08-28 | E-GEOD-69304 | biostudies-arrayexpress
TranscriptomicsTranscriptome during shift of Trichoderma reesei from mycelial growth to asexual sporulation
The asexual spore or conidium plays a critical role in the life cycle of many filamentous fungi, being the primary means for dispersion in the environment. To investigate the transcriptional changes taking place during the sporulation phase in T. reesei, which culminates with the production of the c...
ORGANISM(S): Hypocrea jecorina 
2011-12-08 | E-GEOD-27471 | biostudies-arrayexpress
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