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ProteomicsQuantitative Proteomics Identifies Protein Tyrosine Phosphatase 1B as Modulator of B Cell Antigen Receptor Signaling
B cell antigen receptor (BCR) signaling is initiated by protein kinases and limited by counteracting phosphatases that currently are less well studied in their regulation of BCR signaling. We here used the B cell line Ramos to identify and quantify human B cell signaling components. Specifically, a ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD024037 | Pride
Bcr signaling Ramos b cells Whole proteome analysis 
ProteomicsQuantitative Proteomics Identifies Protein Tyrosine Phosphatase 1B as Modulator of B Cell Antigen Receptor Signaling
B cell antigen receptor (BCR) signaling is initiated by protein kinases and limited by counteracting phosphatases that currently are less well studied in their regulation of BCR signaling. We here used the B cell line Ramos to identify and quantify human B cell signaling components. Specifically, a ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD024038 | Pride
Bcr signaling Ptp1b knockout Silac Ramos b cells Crispr Whole proteome analysis 
ProteomicsThe yeast peroxisomal proteome at absolute quantitative scale
Peroxisomes are dynamic organelles vital for lipid metabolism and redox homeostasis. In Saccharomyces cerevisiae, the expression of peroxisomal proteins is tightly regulated in response to metabolic conditions. Here, we provide the first absolute quantification of the yeast peroxisomal proteome unde...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-02-16 | PXD069526 | Pride
Saccharomyces cerevisiae  peroxisomes  protein copy numbers  absolute quantification  proteomic ruler  mass spectrometry 
ProteomicsCharting Organellar Importomes by Quantitative Mass Spectrometry - ATOM40 whole cells
Protein import into organelles is essential for all eukaryotes and facilitated by multi-protein translocation machineries. Analyzing whether a protein is transported into an organelle is largely restricted to single constituents. This renders knowledge about imported proteins incomplete, limiting ou...
ORGANISM(S): Trypanosoma brucei 
2017-06-14 | PXD005725 | Pride
Trypanosoma brucei Proteomics Glycosomes Organellar protein import Mitochondria Silac Importomics Rnai-mediated protein knockdown 
ProteomicsDefinition of a high-confidence mitochondrial proteome at quantitative scale_absolute quantification of carbon source-dependent protein expression
Mitochondria perform central functions in cellular bioenergetics, metabolism and signaling and their malfunction has been linked to numerous diseases. The available studies cover only part of the mitochondrial proteome and a separation of core mitochondrial proteins from associated fractions has not...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-06-29 | PXD006146 | Pride
Absolute proteome quantification Saccharomyces cerevisiae 
TranscriptomicsIndices of Tolerance (IOT): Cross-platform biomarkers that identify kidney transplant tolerance
Being able to identify patients in whom immunological tolerance has been established or is developing would allow an individually tailored approach to post-transplant management of kidney allograft recipients. Ex vivo immunological monitoring was performed on samples from five groups of European ren...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-14655 | biostudies-arrayexpress
UnknownInternational Epidemiology of Carbapenemase-Producing Escherichia coli.
Not available
S-EPMC10444003 | biostudies-literature
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