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UnknownCollective dynamics of strain-coupled nanomechanical pillar resonators.
Not available
S-EPMC6868224 | biostudies-literature
ProteomicsMultilevel Omics-Readouts of Perturbation Studies in vitro are Determined by Memory Effects from Subculture
Mass spectrometry-based omics technologies are of increasing relevance for drug discovery. In order to map drug treatments to biological pathways for mode of action (MoA) deconvolution, they rely on the determination of multiple testing corrected significant molecular events. The main contributors t...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD051069 | Pride
Phosphoproteomics Reproducibility Multi-level omics Subculture Arsenic trioxide Mode of action deconvolution Proteomics Perturbation network Eicosadomics 
ProteomicsMultilevel Omics-Readouts of Perturbation Studies in vitro are Determined by Memory Effects from Subculture
Mass spectrometry-based omics technologies are of increasing relevance for drug discovery. In order to map drug treatments to biological pathways for mode of action (MoA) deconvolution, they rely on the determination of multiple testing corrected significant molecular events. The main contributors t...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD039768 | Pride
Phosphoproteomics Reproducibility Multi-level omics Subculture Arsenic trioxide Mode of action deconvolution Proteomics Perturbation network Eicosadomics 
UnknownObserving polarization patterns in the collective motion of nanomechanical arrays.
Not available
S-EPMC9072344 | biostudies-literature
UnknownExtracorporeal photopheresis induces the release of anti-inflammatory fatty acids and oxylipins and suppresses pro-inflammatory sphingosine-1-phosphate.
Not available
S-EPMC11825557 | biostudies-literature
ProteomicsProteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases
Background MAP kinase inhibitor (MAPKi) therapy for BRAF mutated melanoma is characterized by high response rates but also development of drug resistance within a median progression-free survival (PFS) of 9 to 12 months. Understanding mechanisms of resistance and identifying effective therapeutic al...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000082948 | MassIVE
UnknownProteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.
Not available
S-EPMC3458105 | biostudies-literature
UnknownCombating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification
Not available
S-EPMC9688189 | biostudies-literature
UnknownProteomic identification of a marker signature for MAPKi resistance in melanoma.
Not available
S-EPMC6669927 | biostudies-literature
UnknownUnraveling the metastasis-preventing effect of miR-200c in vitro and in vivo.
Not available
S-EPMC11977663 | biostudies-literature
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