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ProteomicsMultilevel Omics-Readouts of Perturbation Studies in vitro are Determined by Memory Effects from Subculture
Mass spectrometry-based omics technologies are of increasing relevance for drug discovery. In order to map drug treatments to biological pathways for mode of action (MoA) deconvolution, they rely on the determination of multiple testing corrected significant molecular events. The main contributors t...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD051069 | Pride
Phosphoproteomics Reproducibility Multi-level omics Subculture Arsenic trioxide Mode of action deconvolution Proteomics Perturbation network Eicosadomics 
ProteomicsMultilevel Omics-Readouts of Perturbation Studies in vitro are Determined by Memory Effects from Subculture
Mass spectrometry-based omics technologies are of increasing relevance for drug discovery. In order to map drug treatments to biological pathways for mode of action (MoA) deconvolution, they rely on the determination of multiple testing corrected significant molecular events. The main contributors t...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD039768 | Pride
Phosphoproteomics Reproducibility Multi-level omics Subculture Arsenic trioxide Mode of action deconvolution Proteomics Perturbation network Eicosadomics 
GenomicsMicroplitis demolitor strain:Queensland-Clemson subculture
Microplitis demolitor strain:Queensland-Clemson subculture Genome sequencing and assembly
PRJNA195937 | ENA
GenomicsAmyelois transitella strain:UIUC subculture of SPIRL-1966
Amyelois transitella strain:UIUC subculture of SPIRL-1966 Genome sequencing and assembly
PRJNA254820 | ENA
UnknownMycobacterium tuberculosis Subculture Results in Loss of Potentially Clinically Relevant Heteroresistance.
Not available
S-EPMC5655066 | biostudies-literature
TranscriptomicsGenome-Wide Transcriptome Analysis Reveals Degeneration Progress of Subculture Cordyceps Militaris
The high frequency strain degeneration during subculture seriously restrict the large-scale production of Cordyceps militaris and industrialized process. In the current study, the high-throughput Illumina sequencing was performed on 6 passages subculture C. militaris strains to obtain the divergence...
ORGANISM(S): Cordyceps militaris 
2019-08-15 | GSE100834 | GEO
UnknownPrevalence of deliberate self harm and attempted suicide within contemporary Goth youth subculture: longitudinal cohort study.
Not available
S-EPMC1458563 | biostudies-literature
UnknownExpression of a Human Prostatic Acid Phosphatase (PAP)-IgM Fc Fusion Protein in Plants Using In vitro Tissue Subculture.
Not available
S-EPMC5329016 | biostudies-literature
UnknownEffects of mating-type ratio imbalance on the degeneration of Cordyceps militaris subculture and preventative measures.
Not available
S-EPMC11243967 | biostudies-literature
UnknownTrypsin-induced proteome alteration during cell subculture in mammalian cells.
Not available
S-EPMC2873939 | biostudies-literature
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