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ProteomicsProteomics analysis of the effect of deletion of PUF3 on yeast via LC-MSMS.
The Puf family of RNA-binding proteins regulate the expression of genes by controlling protein synthesis or stimulating RNA decay. Puf3p is one of six Puf-family members in Saccharomyces cerevisiae. Puf3p has been characterised previously as regulating mRNA decay of nuclear mRNAs that encode for mi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-04-13 | PXD001903 | Pride
Lc-msms Yeast Label-free quantification 
ProteomicsIdentification of protein-protein interactions involving the eIF4E binding proteins Caf20p and Eap1p on yeast via affinity purification and LC-MSMS.
There are multiple translational control pathways. These include pathways involving eIF4E binding proteins (4E-BPs), which inhibit translation by binding and sequestering the 5’ cap binding protein eIF4E away from its partner eIF4G. Saccharomyces cerevisiae has two 4E-BPs: Caf20p and Eap1p. Previou...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-06-29 | PXD001407 | Pride
Lc-msms Affinity purification Yeast Label-free quantification 
ProteomicsProteomics analysis of the effect of deletion and mutation of eIF4E binding proteins Caf20 and Eap1 on yeast via LC-MSMS.
There are multiple translational control pathways. These include pathways involving eIF4E binding proteins (4E-BPs), which inhibit translation by binding and sequestering the 5’ cap binding protein eIF4E away from its partner eIF4G. Saccharomyces cerevisiae has two 4E-BPs: Caf20p and Eap1p; and, mic...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-05-04 | PXD001348 | Pride
Lc-msms Yeast Label-free quantification 
OtherThe yeast La related protein Slf1p is a key activator of translation during the oxidative stress response.
Data from ProteomeXchange, PXD ID: PXD000887. File: 20131025_GP_CK_S2_1in10_01.mzml. Published as part of PLoS Genet. 2015 Jan 8;11(1):e1004903 . From the Abstract: {{i}} The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p and Sro9p are ...
ORGANISM(S): Yeast 
GPM32310018418 | GPMDB
Resource Reanalysis 
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