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ProteomicsPotent anti-SARS-CoV-2 activity by the natural product gallinamide A and analogues via inhibition of cathepsin L
The emergence of SARS-CoV-2 in late 2019, and the subsequent COVID-19 pandemic, has led to substantial mortality together with mass global disruption. There is an urgent need for novel antiviral drugs for therapeutic or prophylactic application. Cathepsin L is a key host cysteine protease utilized b...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027300 | Pride
Mrc5 Sars-cov-2 Covid Cathepsin l Veroe6 Gallinamide a Hek293 
UnknownSpatial immunophenotypes orchestrate prognosis in triple-negative breast cancer with Miller-Payne grade 4 following neoadjuvant chemotherapy.
Not available
S-EPMC10338497 | biostudies-literature
TranscriptomicsDifferentially expressed genes after treatment with chemotherapy in breast cancer and their correlation with pathologic bad response (Miller & Payne grades 1 and 2)
The aim of this study was to compare the gene expression profile changes breast tumors after the treatment with Anthracyclines and Taxanes. To this end, an oligonucleotide microarray was performed (AffymetrixM-bM-^@M-^Ys HG-U133 Plus 2.0 array). This gene expression study was carried out on the biop...
ORGANISM(S): Homo sapiens 
2012-12-12 | E-GEOD-28826 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes after treatment with chemotherapy in breast cancer and their correlation with pathologic mid-response (Miller & Payne grade 3)
The aim of this study was to compare the gene expression profile changes breast tumors after the treatment with Anthracyclines and Taxanes. To this end, an oligonucleotide microarray was performed (AffymetrixM-bM-^@M-^Ys HG-U133 Plus 2.0 array). This gene expression study was carried out on the biop...
ORGANISM(S): Homo sapiens 
2012-12-12 | E-GEOD-28583 | biostudies-arrayexpress
TranscriptomicsExpression profiling by array of Salmonella enterica serovar Typhimurium (SL1344) qseC mutant x wild type
“Stress, survival and virulence: the multi-faceted host/microbial interactions.” Bacteria employ epinephrine and norepinephrine, which converge to distinct bacterial crucial processes, like survival and pathogenicity. A novel stress periplasmic membrane protein belonging to previously described BOF...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 
2012-05-31 | E-GEOD-38353 | biostudies-arrayexpress
TranscriptomicsDifferentially expressed genes after treatment with chemotherapy in breast cancer and their correlation with pathologic good response (Miller & Payne grades 4 and 5)
The aim of this study was to compare the gene expression profile changes breast tumors after the treatment with Anthracyclines and Taxanes. To this end, an oligonucleotide microarray was performed (AffymetrixM-bM-^@M-^Ys HG-U133 Plus 2.0 array). This gene expression study was carried out on the biop...
ORGANISM(S): Homo sapiens 
2012-12-12 | E-GEOD-28694 | biostudies-arrayexpress
UnknownPotent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.
Not available
S-EPMC8577376 | biostudies-literature
UnknownElectron tomography provides a direct link between the Payne effect and the inter-particle spacing of rubber composites.
Not available
S-EPMC4260230 | biostudies-literature
UnknownL-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway.
Not available
S-EPMC3447780 | biostudies-literature
UnknownDifferential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells.
Not available
S-EPMC5067213 | biostudies-literature
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