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Multi-virus CRISPR screening data in VeroE6 cells
SARS-CoV-2 infected and uninfected VeroE6 and A549-ACE2: Bemcentinib and liposome treatments
VeroE6 or A549-ACE2 cells were treated with inhibitors of phosphatidylserine receptors and infected with SARS-CoV-2.
ORGANISM(S): Chlorocebus aethiops Homo sapiens Severe acute respiratory syndrome coronavirus 2 
2021-06-26 | GSE178942 | GEO
RNA Sequencing of VeroE6 cells infected with SARS-CoV-2 in presence and absence of GYY4137
Viruses modulate various aspects of host physiology, including carbon metabolism, redox balance, and mitochondrial bioenergetics, to acquire the building blocks for replication and regulate the immune response. Understanding newer ways of how SARS-CoV-2 alters host redox metabolism, carbon metabolis...
ORGANISM(S): Chlorocebus sabaeus 
2025-04-15 | GSE283665 | GEO
The emergence of SARS-CoV-2 in late 2019, and the subsequent COVID-19 pandemic, has led to substantial mortality together with mass global disruption. There is an urgent need for novel antiviral drugs for therapeutic or prophylactic application. Cathepsin L is a key host cysteine protease utilized b...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027300 | Pride
We report the results of CRISPR survival screens in the context of multiple viral infections. Two sgRNA pools were used: one targeting the SARS-CoV-2 RNA interactome proteins, and one targeting mitochondrially-related proteins.
ORGANISM(S): Chlorocebus sabaeus 
2021-02-24 | GSE167334 | GEO
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