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MetabolomicsIntegrated Multi-omics Analysis Identifies PPAR Signaling Network Associations with Metabolic-Immune Dysregulation and Intestinal Injury in PDCoV-Infected Piglets

Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that causes severe diarrhea and high mortality in neonatal piglets and has demonstrated the capacity to infect human cells. However, the host response networks that govern disease outcome remain poorly understood. Here, we perfor...

2026-04-15 | MTBLS14236 | MetaboLights
ProteomicsIntegrated Multi-omics Analysis Identifies PPAR Signaling Network Associations with Metabolic-Immune Dysregulation and Intestinal Injury in PDCoV-Infected Piglets
Porcine deltacoronavirus (PDCoV) is an emerging enteric coronavirus that causes severe diarrhea and high mortality in neonatal piglets and has demonstrated the capacity to infect human cells. However, the host response networks that govern disease outcome remain poorly understood. Here, we performed...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2026-04-21 | PXD076809 | Pride
Pdcov Jejunum 
GenomicsPorcine deltacoronavirus strain:PDCoV-ZJHZ2024
PDCoV Genome sequencing and assembly
PRJNA1259176 | ENA
GenomicsExpression profiles of microRNAs in ST cells uninfected or infected by PDCoV
Expression profiles of microRNAs in ST cells uninfected or infected by PDCoV
PRJNA736691 | ENA
ProteomicsPorcine intestinal epithelial cells
Porcine deltacoronavirus (PDCoV) is an emerging pathogen of swine belonging to family Coronaviridae, genus Deltacoronavirus. PDCoV predominantly infects the porcine intestinal epithelial cells (IPECs) causing severe diarrhea and/or vomiting, dehydration, and death in piglets. However, there are no r...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-10-19 | PXD019975 | Pride
Porcine intestine lc-ms/ms 
ProteomicsNovel interacting proteins identified by tandem affinity purification and mass spectrometry associated with IFITM3 protein during PDCoV infection
To clarify novel roles of IFITM3 during PDCoV infection，host cell proteins that interact with IFITM3 were screened by tandem affinity purification coupled with mass spectrometry (TAP/MS) in ST cell line stably expressing IFITM3 via lentivirus.
ORGANISM(S): Sus Scrofa Domesticus 
2023-12-02 | PXD047480 |
GenomicsExpression profiles of circular RNAs in ST cells uninfected or infected by PDCoV
Expression profiles of circular RNAs in ST cells uninfected or infected by PDCoV
PRJNA613287 | ENA
TranscriptomicsIntegrated analysis of transcriptome and proteome reveal that PDCoV infection induces autophagy-dependent ferroptosis to facilitate viral replication
Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus that causes severe diarrhea in swine industries worldwide. However, the interactions between PDCoV and host cells remain poorly understood. In this study, we employed transcriptomic and proteomic analyses to investigate hos...
ORGANISM(S): Sus scrofa 
2026-05-27 | GSE302490 | GEO
GenomicsExpression profiles of microRNAs in ST cells uninfected or infected by PDCoV
mircoRNAs (miRNAs) participate in regulating many biological processes. However, their roles in PDCoV pathogenicity are largely unknown. Here, we analyzed the expression profile of miRNAs in ST cells uninfected or infected by PDCoV by high-throughput sequencing
ORGANISM(S): Sus scrofa 
2021-11-04 | GSE176550 | GEO
GenomicsExpression profiles of long noncoding RNAs and mRNAs in ST cells infected by PDCoV
Expression profiles of long noncoding RNAs and mRNAs in ST cells infected by PDCoV
PRJNA563163 | ENA
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