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ProteomicsBiomarkers of pediatric cataracts: a proteomics analysis of aqueous fluid
Abstract Background: Cataracts are among the most common causes of childhood vision loss worldwide. This study seeks to identify differentially expressed proteins in the aqueous humor of pediatric cataract patients. Methods: Samples of aqueous humor were collected from pediatric and adult cataract...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD022529 | Pride
Q-exactive Pediatric cataracts  proteomics  aqueous humor Lfq 
TranscriptomicsGenome-wide analysis of Tdrd7 knockdown in lens epithelial-derived cell line 21EM15
Analysis of Tdrd7 deficiency in mouse lens epithelial-derived cell line at gene expression level. The hypothesis tested was that Tdrd7 is involved in post-transcriptional control of gene expression in the lens. Results provide evidence for differential regulation of genes involved in lens homeostasi...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-25774 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of 4-day old (P4) Tdrd7 null mouse lens
Analysis of Tdrd7 deficiency in mouse lens epithelial-derived cell line at gene expression level. The hypothesis tested was that Tdrd7 is involved in post-transcriptional control of gene expression in the lens. Results provide evidence for differential regulation of genes involved in lens homeostasi...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-25775 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of 1 month old (P30) Tdrd7 null mouse lens
Analysis of Tdrd7 deficiency in mouse lens epithelial-derived cell line at gene expression level. The hypothesis tested was that Tdrd7 is involved in post-transcriptional control of gene expression in the lens. Results provide evidence for differential regulation of genes involved in lens homeostasi...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-25776 | biostudies-arrayexpress
UnknownBiomarkers of Pediatric Cataracts: A Proteomics Analysis of Aqueous Fluid.
Not available
S-EPMC10219433 | biostudies-literature
UnknownWhole Exome Sequencing of 20 Spanish Families: Candidate Genes for Non-Syndromic Pediatric Cataracts.
Not available
S-EPMC10380485 | biostudies-literature
TranscriptomicsRNA-seq of human lens with cataracts, alopecia, & microdontia
The genetic daignosis of a pediatric patient with primary symptoms bilateral cataracts, alopecia and microdontia could not be obtained through standard genetic tests. We sought to obtain the diagnosis of this rare syndrome through RNA-seq of the cataract lens against an age-matched donor lens.
ORGANISM(S): Homo sapiens 
2021-12-12 | GSE124121 | GEO
UnknownManagement of cataracts and ectopia lentis in children: Practice patterns of pediatric ophthalmologists in India.
Not available
S-EPMC5621263 | biostudies-literature
UnknownDistinct gene expression profiles underlie morphological and etiological differences in pediatric cataracts.
Not available
S-EPMC10391435 | biostudies-literature
UnknownInterocular anatomical and visual functional differences in pediatric patients with unilateral cataracts.
Not available
S-EPMC5094053 | biostudies-literature
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