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TranscriptomicsTranscription profiling of human T-ALL patients at diagnosis and relapse
A "Cartes d'Identite des Tumeurs" (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). 104 samples; Affymetrix U133A micro-arrays.

Ninety two patients with T-ALL were diagnosed and treated at Saint-Louis hospital, Paris. Seven patients were studied a...
ORGANISM(S): Homo sapiens 
2005-04-15 | E-MEXP-313 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human gamma-secretase inhibitor-sensitive and -resistant T-ALL cell lines
Gain-of-function mutations in NOTCH1 are common in T-cell lymphoblastic leukemias making this receptor a promising target for drugs such as gamma-secretase inhibitors, which block a proteolytic cleavage required for NOTCH1 activation. However, the enthusiasm for these therapies has been tempered by ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5682 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of T-ALL cell lines treated with gamma-secretase inhibitor
Gain-of-function mutations in NOTCH1 are common in T-cell lymphoblastic leukemias making this receptor a promising target for drugs such as gamma-secretase inhibitors (GSI), which block a proteolytic cleavage required for NOTCH1 activation. However, the enthusiasm for these therapies has been temper...
ORGANISM(S): Homo sapiens 
2008-08-20 | E-GEOD-5716 | biostudies-arrayexpress
ProteomicsBRAF mutations disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mouse and humans
Germline mutations in BRAF and other components of the Mitogen-Activated Protein Kinase (MAPK) pathway are associated with the congenital syndromes collectively known as RASopathies. Here, we report the association of Septo-Optic Dysplasia (SOD) including hypopituitarism and Cardio-Facio-Cutaneous (...
ORGANISM(S): Homo sapiens (Human) 
2020-11-17 | PXD018190 | Pride
Label free Ksea Phosphoproteomics Human Rasopathies Braf Lcms 
UnknownA Common Genetic Origin for Early Farmers from Mediterranean Cardial and Central European LBK Cultures.
Not available
S-EPMC4652622 | biostudies-literature
TranscriptomicsRNA-seq of leaf tissue from four genotypes of Lathyrus sativus infected with the Erysiphe pisi
Four L. sativus accessions, exhibiting varying levels of resistance to E. pisi (resistant, partially resistant, partially susceptible, and susceptible), were analysed using dual RNA-seq. Leaflets from each plant were sampled at 0 (non-inoculated), 6, 12, 24, 48, and 72 hours after inoculation. Forty...
ORGANISM(S): Lathyrus sativus 
2025-02-28 | E-MTAB-14647 | biostudies-arrayexpress
TranscriptomicsHuman in vivo nutrigenomic effect of olive oil
Olive oil is protective against risk factors for cardiovascular and cancer diseases. A nutrigenomic approach was performed to assess whether olive oil, the main fat of the Mediterranean diet modifies the gene expression in human peripheral blood mononuclear cells. Six healthy male volunteers ingeste...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10590 | biostudies-arrayexpress
UnknownKey Factors Associated With Pulmonary Sequelae in the Follow-Up of Critically Ill COVID-19 Patients.
Not available
S-EPMC9824938 | biostudies-literature
UnknownEffect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study.
Not available
S-EPMC10129133 | biostudies-literature
UnknownRemdesivir and survival outcomes in critically ill patients with COVID-19: A multicentre observational cohort study.
Not available
S-EPMC9804970 | biostudies-literature
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