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UnknownEco-friendly stability-indicating RP-HPTLC method for sildenafil analysis, characterization and biological evaluation of its oxidized stress degradation product.
Not available
S-EPMC8319155 | biostudies-literature
UnknownA weak acid-responsive porous polyelectrolyte membrane enables the high efficiency of a zinc anode interface.
Not available
S-EPMC12231561 | biostudies-literature
TranscriptomicsEstrogen induces global reorganization of chromatin structure in human breast cancer cells
In the cell nucleus, each chromosome is confined to a chromosome territory. This spatial organization of chromosomes plays a crucial role in gene regulation and genome stability. Recently an additional level of organization has been discovered at the chromosome scale: the spatial segregation into ...
ORGANISM(S): Homo sapiens 
2013-10-25 | E-GEOD-51687 | biostudies-arrayexpress
UnknownStructurally Diverse Alkaloids from the Seeds of Peganum harmala.
Not available
S-EPMC5518681 | biostudies-literature
Proteomics4D label free phosphorylation modification omics of 60 human esophageal cancer tissue samples
Phosphoproteome analysis of clinical tissue samples is important in the precision medicine research. Therefore, we used LC-MS/MS to systematically analyze the differential phosphorylation levels of 20 ESCC tumor tissues, paired normal tissue and lymph node metastatic tissue.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD051858 | Pride
Esophageal cancer Phosphorylation Human Lc-ms/ms 
ProteomicsQuantitative Khib proteomic analyses of 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN)
To obtain the global landscape of Khib in ESCC metastasis, 20 cases of primary ESCC tumor tissue (T), matched normal tissue (N) and lymph node metastatic tissue (LN) were subjected to quantitative Khib proteomic analyses.
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD038252 | Pride
Proteomics Lysine 2-hydroxyisobutyrylation Cancer metastasis 
TranscriptomicsThe conserved organization of the human and mouse transcriptomes
We characterized by RNA-seq the transcriptional profiles of a large and heterogeneous collection of mouse tissues, augmenting the mouse transcriptome with thousands of novel transcript candidates. Comparison with transcriptome profiles obtained in human cell lines reveals substantial conservation of...
ORGANISM(S): Homo sapiens 
2014-11-20 | E-GEOD-49417 | biostudies-arrayexpress
TranscriptomicsEstrogen-mediated Epigenetic Repression of Large Chromosomal Regions through DNA Looping
The current concept of epigenetic repression is based on one repressor unit corresponding to one silent gene. This notion, however, cannot adequately explain concurrent silencing of multiple loci observed in large chromosome regions. The long-range epigenetic silencing (LRES) can be a frequent occur...
ORGANISM(S): Homo sapiens 
2010-04-29 | E-GEOD-21068 | biostudies-arrayexpress
GenomicsNational Heart Lung and Blood Institute Exome sequencing in SCID

Analysis of the molecular etiologies of severe combined immunodeficiency (SCID) has led to important insights into the control of immune cell development. Most cases of SCID result from either X-linked or autosomal recessive inheritance of mutations in a known causative gene. However, in some cas...

phs000479.v1.p1 | EGA
GenomicsHypermethylation in the ZBTB20 gene is associated with major depressive disorder
Genome-wide MeDIP-Sequencing of 23 monozygotic twin pairs (n=46) from Australia discordant for major depressive disorder (MDD). MeDIP-seq of 23 monozygotic twin pairs discordant for major depressive disorder. MZ twin pairs were compared to identify significantly differently methylated sites associat...
ORGANISM(S): Homo sapiens 
2014-01-25 | E-GEOD-54370 | biostudies-arrayexpress
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