Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human CD43+ cells isolated from myelodysplastic syndrome patients and normal controls reveals involvement of interferon-stimulated genes and correlation to FAB subtype and karyotype.
55 patients with MDS and 11 healthy controls were included in the study. At the time of investigation, 18 patients had RA, 19 RARS and 18 RAEB. The RAEB group was further subdivided into RAEB1 and RAEB2 for a selected part of the analysis. Bone marrow samples were obtained and CD34+ cells isolated f...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4619 | biostudies-arrayexpress
TranscriptomicsAlpha Thalassaemia Myelodysplasia Syndrome (ATMDS)
A 10K cDNA microarray was used to compare granulocyte RNA from one ATMDS patient to pooled granulocyte RNA from 7 healthy controls.
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-445 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of CD34+ cells from the bone marrow of Myelodysplastic syndrome patients and healthy controls
In order to gain insight into the molecular pathogenesis of the myelodysplastic syndromes (MDS), we performed global gene expression profiling and pathway analysis on the hematopoietic stem cells (HSC) of 183 MDS patients as compared with the HSC of 17 healthy controls. The most significantly deregu...
ORGANISM(S): Homo sapiens 
2010-03-24 | E-GEOD-19429 | biostudies-arrayexpress
TranscriptomicsMyelodysplastic Syndromes (MDS) and Acute Myeloid Leukaemia (AML)
A 10K cDNA microarray was used to compare neutrophil RNA from 21 MDS patient and 2 AML patients to pooled neutrophil RNA from 7 healthy controls.
ORGANISM(S): Homo sapiens 
2005-01-09 | E-GEOD-971 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls
The splicing factor SF3B1 is the most commonly mutated gene in the myelodysplastic syndromes (MDS), particularly in patients with refractory anemia with ring sideroblasts (RARS). MDS is a disorder of the hematopoietic stem cell and we thus studied the transcriptome of CD34+ cells from MDS patients w...
ORGANISM(S): Homo sapiens 
2014-11-22 | E-GEOD-63569 | biostudies-arrayexpress
UnknownRecent Advances in the 5q- Syndrome.
Not available
S-EPMC4450650 | biostudies-literature
UnknownA miRNA screening identifies miR-192-5p as associated with response to azacitidine and lenalidomide therapy in myelodysplastic syndromes.
Not available
S-EPMC9940408 | biostudies-literature
TranscriptomicsExpression data from human hematopoietic stem and progenitor compartments from patients with acute myeloid leukemia with normal karyotype and healthy controls
We applied a novel approach of parallel transcriptional analysis of multiple, highly fractionated stem and progenitor populations from patients with acute myeloid leukemia (AML) and a normal karyotype. We isolated phenotypic long-term HSC (LT-HSC), short-term HSC (ST-HSC), and committed granulocyte-...
ORGANISM(S): Homo sapiens 
2012-09-05 | E-GEOD-35008 | biostudies-arrayexpress
UnknownMeta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration.
Not available
S-EPMC2495035 | biostudies-literature
UnknownIL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells.
Not available
S-EPMC4432009 | biostudies-literature
Sort   by:  
 Page size