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GenomicsLoss of H3K27 monomethylation leads to DNA-methylation-independent release of gene silencing
Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications including DNA methylation, histone 3 dimethylation at lysine 9 (H3K9me2), and monomethylation at lysine 27 (H3K27me1). The enzymes catalyzing DNA methylation and H3K9me2 have been identified and muta...
ORGANISM(S): Arabidopsis thaliana 
2009-05-31 | E-GEOD-16071 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of the transcriptome from Sulfur Deprivation Chlamydomonas cells
The Chlamydomonas reinhardtii transcriptome was characterized from nutrient-replete and sulfur-depleted wild-type and snrk2.1 mutant cells; the mutant is null for the regulatory serine-threonine kinase SNRK2.1, which is required for acclimation to sulfur deprivation. The transcriptome analyses invol...
ORGANISM(S): Chlamydomonas reinhardtii 
2010-07-07 | E-GEOD-17970 | biostudies-arrayexpress
TranscriptomicsThe Path to Triacylglyceride Obesity in the sta6 Strain of Chlamydomonas reinhardtii
When the sta6 (starch-null) strain of the green microalga Chlamydomonas reinhardtii is nitrogen-starved in acetate and then "boosted" after two days with additional acetate, the cells become "obese" after eight days, with triacylglyceride-filled lipid bodies filling their cytopla...
ORGANISM(S): Chlamydomonas reinhardtii 
2014-03-09 | E-GEOD-55253 | biostudies-arrayexpress
TranscriptomicsWidespread Use of Non-Productive Alternative Splice Sites in Saccharomyces cerevisiae
Using RNA-Seq analysis of nonsense-mediated mRNA decay (NMD) mutant strains, we show that many Saccharomyces cerevisiae intron-containing genes exhibit usage of alternative splice sites, but most transcripts generated by splicing from these sites are non-functional because they introduce premature t...
ORGANISM(S): Saccharomyces cerevisiae BY4741 
2014-02-21 | E-GEOD-55213 | biostudies-arrayexpress
TranscriptomicsA revised mineral nutrient supplement increases biomass and growth rate in Chlamydomonas reinhardtii
Interest in exploiting algae as a biofuel source and the role of nutrient deficiency in inducing triacylglyceride (TAG) accumulation in cells necessitates a strategy to efficiently formulate species-specific culture media that can be easily manipulated. Using the reference organism Chlamydomonas rei...
ORGANISM(S): Chlamydomonas reinhardtii 
2011-10-23 | E-GEOD-25622 | biostudies-arrayexpress
GenomicsGenome-wide erasure of DNA methylation in mouse primordial germ cells is affected by Aid deficiency
Epigenetic reprogramming including demethylation of DNA occurs in mammalian primordial germ cells (PGCs) and in early embryos, and is important for the erasure of imprints and epimutations, and the return to pluripotency. The extent of this reprogramming and its molecular mechanisms are poorly under...
ORGANISM(S): Mus musculus 
2010-01-26 | E-GEOD-19960 | biostudies-arrayexpress
TranscriptomicsSINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii
To identify components involved in the signal transduction and activation of the singlet oxygen-mediated response, a mutant selection was performed. This led to the isolation of the singlet oxygen resistant 1 (sor1) mutant, which is more tolerant to singlet oxygen-producing chemicals and shows a con...
ORGANISM(S): Chlamydomonas reinhardtii 
2012-04-03 | E-GEOD-33548 | biostudies-arrayexpress
UnknownRobust and Persistent B- and T-Cell Responses after COVID-19 in Immunocompetent and Solid Organ Transplant Recipient Patients.
Not available
S-EPMC8621286 | biostudies-literature
TranscriptomicsGenome wide profiling of H3K9me2 in Arabidopsis thaliana
The objective of the study is to profile histone H3 lysine nine di-methylation (H3K9me2) in Arabidopsis thaliana and to correlate it with DNA methylation. We constructed a high-resolution genome-wide map of H3K9me2 methylation by using native chromatin immunoprecipitation coupled with HD2 whole geno...
ORGANISM(S): Arabidopsis thaliana 
2010-06-19 | E-GEOD-12383 | biostudies-arrayexpress
GenomicsA Genome-wide Chronological Study of Gene Expression and Two Histone Modifications, H3K4me3 and H3K9ac, during Developmental Leaf Senescence [ChIP-seq]
The genome-wide abundance of two histone modifications, H3K4me3 and H3K9ac, both associated with actively expressed genes, was monitored in Arabidopsis thaliana leaves at different time points during developmental senescence, along with expression in the form of RNA-seq data. H3K9ac and H3K4me3 mark...
ORGANISM(S): Arabidopsis thaliana 
2015-04-11 | E-GEOD-67776 | biostudies-arrayexpress
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