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ProteomicsStructural proteomic analysis of folding intermediates of FLuc on the human ribosome
bRNC HDX-MS: Protein biogenesis begins on the ribosome where nascent chains are expressed vectorially from their N- to C-terminus, and start to fold as mRNA is translated. How the context of protein synthesis influences protein folding is poorly understood, especially in eukaryotes. Here we describe...
ORGANISM(S): Escherichia coli 
2025-08-11 | PXD055476 | Pride
Ribosome Nascent chain Bacteria Hdx-ms Firefly luciferase Protein synthesis Protein folding 
ProteomicsStructural proteomic analysis of folding intermediates of FLuc on the human ribosome
hRNC HDX-MS: Protein biogenesis begins on the ribosome where nascent chains are expressed vectorially from their N- to C-terminus, and start to fold as mRNA is translated. How the context of protein synthesis influences protein folding is poorly understood, especially in eukaryotes. Here we describe...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD055280 | Pride
Human Ribosome Nascent chain Hdx-ms Firefly luciferase Protein synthesis Protein folding 
ProteomicsStructural proteomic analysis of folding intermediates of FLuc on the human ribosome
hRNC Proteomics - Protein biogenesis begins on the ribosome where nascent chains are expressed vectorially from their N- to C-terminus, and start to fold as mRNA is translated. How the context of protein synthesis influences protein folding is poorly understood, especially in eukaryotes. Here we des...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD055069 | Pride
Human Ribosome Nascent chain Proteomics Firefly luciferase Protein synthesis Protein folding 
ProteomicsStructural proteomic analysis of folding intermediates of FLuc on the human ribosome
bRNC Proteomics - Protein biogenesis begins on the ribosome where nascent chains are expressed vectorially from their N- to C-terminus, and start to fold as mRNA is translated. How the context of protein synthesis influences protein folding is poorly understood, especially in eukaryotes. Here we des...
ORGANISM(S): Escherichia coli 
2025-08-11 | PXD055060 | Pride
Ribosome Nascent chain E. coli Bacteria Proteomics Firefly luciferase Protein synthesis Protein folding 
ProteomicsStructural proteomic analysis of folding intermediates of FLuc on the human ribosome
hRNC XL-MS: Protein biogenesis begins on the ribosome where nascent chains are expressed vectorially from their N- to C-terminus, and start to fold as mRNA is translated. How the context of protein synthesis influences protein folding is poorly understood, especially in eukaryotes. Here we describe ...
ORGANISM(S): Homo sapiens (Human) 
2025-08-11 | PXD055251 | Pride
Human Ribosome Cotranslational Xl-ms Firefly luciferase Protein folding 
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