Sort   by:  
 Page size 
We introduce high-throughput and massive paired-end mapping (PEM), a large-scale genome sequencing method to identify SVs 3 kb or larger that combines the rescue and capture of paired-ends of 3 kb fragments, massive 454 Sequencing, and a computational approach to map DNA reads onto a reference genom...
ORGANISM(S): Homo sapiens 
Genomics
PEM-seq
Liver models that closely mimic the in vivo microenvironment are central for understanding liver functions, capabilities, and intercellular communication processes. Whereas hepatocyte monolayers de-differentiate after only a few days in culture, constructs consisting of hepatocytes and non-parenchym...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-07-06 | PXD002491 | Pride
Cohesin modulates DNA replication to preserve genome integrity [PEM-seq]
PEM-seq
2021-07-07 | OEX00012198 | NODE
To unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis, testicular gene expression was compared in mice with a Sertoli cell-selective androgen receptor knockout (SCARKO) and littermate controls on postnatal d 10. At this age testicular cell composition is still com...
ORGANISM(S): Mus musculus 
Malignant Peritoneal Mesothelioma (PeM) is a rare but frequently fatal cancer that originates from the peritoneal lining of the abdomen. Standard treatment of PeM is limited to cytoreductive surgery and/or chemotherapy, and no targeted therapies for PeM yet exist. This study performs comprehensive i...
ORGANISM(S): Homo sapiens (Human) 
2018-12-11 | PXD008873 | Pride
Minimizing far-extending chromatin perturbation in genome editing preserves stem cell identity [PEM-seq]
Sort   by:  
 Page size